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Diabetes Care：婴儿期肠道病毒感染或增胰岛自身免疫风险

2012-11-07 佚名 中华医学会糖尿病学分会

肠道病毒感染胰岛自身免疫风险婴儿期
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　　来自美国的DAISY研究提示，婴儿期肠病毒或轮状病毒感染可能增加胰岛自身免疫（IA，即胰岛素、谷氨酸脱羧酶或酪氨酸磷酸酶抗体阳性）风险。（Diabetes Care.2012年10月5日在线版） 　　该研究搜集了1729例儿童9个月内的患病记录，其中1174例无1型糖尿病家族史，555例的一级亲属为1型糖尿病患者。结果显示，109名儿童持续存在IA。胃肠道疾病患病次数越多，IA风险

　　来自美国的DAISY研究提示，婴儿期肠病毒或轮状病毒感染可能增加胰岛自身免疫（IA，即胰岛素、谷氨酸脱羧酶或酪氨酸磷酸酶抗体阳性）风险。（Diabetes Care.2012年10月5日在线版）

　　该研究搜集了1729例儿童9个月内的患病记录，其中1174例无1型糖尿病家族史，555例的一级亲属为1型糖尿病患者。结果显示，109名儿童持续存在IA。胃肠道疾病患病次数越多，IA风险越大，但仅见于4个月内或7个月以上摄入含麸质的谷物的儿童（HR分别为1.37和1.12）。研究者发现，上呼吸道症状、呼吸道疾病或发热与IA无关。

　　链接：

Snell-Bergeon JK, Smith J, Dong F, Barón AE, Barriga K, Norris JM, Rewers M.Early Childhood Infections and the Risk of Islet Autoimmunity: The Diabetes Autoimmunity Study in the Young (DAISY).Diabetes Care. 2012 Oct 5


 

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    2013-06-24 baoya

    #胰岛#

    0

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    2013-09-23 ms5439512287675881

    #BET#

    0

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    2013-07-12 ms9608593228839890

    #DIA#

    0

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    2013-02-17 木头人513

    #Diabetes#

    0

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    2012-11-09 liye789132253

    #肠道病毒#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1749380, encodeId=03de1e493803f, content=<a href='/topic/show?id=be7c8385345' target=_blank style='color:#2F92EE;'>#胰岛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83853, encryptionId=be7c8385345, topicName=胰岛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a7a536274692, createdName=baoya, createdTime=Mon Jun 24 12:04:00 CST 2013, time=2013-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759209, encodeId=aa131e5920983, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Mon Sep 23 11:04:00 CST 2013, time=2013-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1636585, encodeId=c1ff1636585e6, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Fri Jul 12 06:04:00 CST 2013, time=2013-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1901018, encodeId=fcd91901018e9, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Sun Feb 17 16:04:00 CST 2013, time=2013-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1454600, encodeId=e1b71454600ae, content=<a href='/topic/show?id=2bd981e071f' target=_blank style='color:#2F92EE;'>#肠道病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81707, encryptionId=2bd981e071f, topicName=肠道病毒)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=2a9a5579963, createdName=liye789132253, createdTime=Fri Nov 09 01:04:00 CST 2012, time=2012-11-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1614098, encodeId=6f09161409858, content=<a href='/topic/show?id=a6824506923' target=_blank style='color:#2F92EE;'>#婴儿期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45069, encryptionId=a6824506923, topicName=婴儿期)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e85919488444, createdName=108807375_62823133, createdTime=Fri Nov 09 01:04:00 CST 2012, time=2012-11-09, status=1, ipAttribution=)]
    2012-11-09 108807375_62823133

    #婴儿期#

    0