Am J Cardiol:GRACE评分可准确评估ACS危险

2012-11-16 高晓方译 医学论坛网

  加拿大学者的一项研究表明,与确诊急性冠脉综合征(ACS)相比,可能ACS患者的基线GRACE风险评估较高,但在入院24小时内较少接受循证性治疗。论文于2012年11月5日在线发表于《美国心脏病学杂志》(Am J Cardiol)。   此项研究共纳入16618例临床诊断为ACS的患者,并就人口统计学和临床特征、心脏操作应用、GRACE风险评分预测准确性以及院内转归对以确诊

  加拿大学者的一项研究表明,与确诊急性冠脉综合征(ACS)相比,可能ACS患者的基线GRACE风险评估较高,但在入院24小时内较少接受循证性治疗。论文于2012年11月5日在线发表于《美国心脏病学杂志》(Am J Cardiol)。

  此项研究共纳入16618例临床诊断为ACS的患者,并就人口统计学和临床特征、心脏操作应用、GRACE风险评分预测准确性以及院内转归对以确诊和可能ACS作为入院诊断的患者进行比较。

  结果显示,已确诊和可能ACS作为最初诊断的患者分别为11152和5466例。可能ACS患者的GRACE风险评分较高,就诊前24小时内较少接受阿司匹林、氯吡格雷、肝素或β受体阻滞剂治疗,并且接受左室功能评估、应激试验、心脏导管治疗和经皮冠脉介入治疗(PCI)的可能性较低。可能ACS患者的院内心肌梗死和心衰发生率较高。在两组患者中GRACE风险评分均可有效预测院内死亡率。

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1781606, encodeId=00621e8160645, content=<a href='/topic/show?id=5db8409ed8' target=_blank style='color:#2F92EE;'>#Cardiol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4097, encryptionId=5db8409ed8, topicName=Cardiol)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Wed May 29 07:07:00 CST 2013, time=2013-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1655660, encodeId=e613165566064, content=<a href='/topic/show?id=2a011829d7' target=_blank style='color:#2F92EE;'>#ACE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1829, encryptionId=2a011829d7, topicName=ACE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=635024767990, createdName=shanyongle, createdTime=Wed Jun 12 19:07:00 CST 2013, time=2013-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279006, encodeId=a43612e9006a4, content=<a href='/topic/show?id=316d1882bc' target=_blank style='color:#2F92EE;'>#ACS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1882, encryptionId=316d1882bc, topicName=ACS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=102a153, createdName=yaanren, createdTime=Sun Nov 18 06:07:00 CST 2012, time=2012-11-18, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1781606, encodeId=00621e8160645, content=<a href='/topic/show?id=5db8409ed8' target=_blank style='color:#2F92EE;'>#Cardiol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4097, encryptionId=5db8409ed8, topicName=Cardiol)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Wed May 29 07:07:00 CST 2013, time=2013-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1655660, encodeId=e613165566064, content=<a href='/topic/show?id=2a011829d7' target=_blank style='color:#2F92EE;'>#ACE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1829, encryptionId=2a011829d7, topicName=ACE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=635024767990, createdName=shanyongle, createdTime=Wed Jun 12 19:07:00 CST 2013, time=2013-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279006, encodeId=a43612e9006a4, content=<a href='/topic/show?id=316d1882bc' target=_blank style='color:#2F92EE;'>#ACS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1882, encryptionId=316d1882bc, topicName=ACS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=102a153, createdName=yaanren, createdTime=Sun Nov 18 06:07:00 CST 2012, time=2012-11-18, status=1, ipAttribution=)]
    2013-06-12 shanyongle
  3. [GetPortalCommentsPageByObjectIdResponse(id=1781606, encodeId=00621e8160645, content=<a href='/topic/show?id=5db8409ed8' target=_blank style='color:#2F92EE;'>#Cardiol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4097, encryptionId=5db8409ed8, topicName=Cardiol)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Wed May 29 07:07:00 CST 2013, time=2013-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1655660, encodeId=e613165566064, content=<a href='/topic/show?id=2a011829d7' target=_blank style='color:#2F92EE;'>#ACE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1829, encryptionId=2a011829d7, topicName=ACE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=635024767990, createdName=shanyongle, createdTime=Wed Jun 12 19:07:00 CST 2013, time=2013-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279006, encodeId=a43612e9006a4, content=<a href='/topic/show?id=316d1882bc' target=_blank style='color:#2F92EE;'>#ACS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1882, encryptionId=316d1882bc, topicName=ACS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=102a153, createdName=yaanren, createdTime=Sun Nov 18 06:07:00 CST 2012, time=2012-11-18, status=1, ipAttribution=)]
    2012-11-18 yaanren