Diabetes Care:降低糖尿病风险策略不分种族

2012-07-31 张一宸 医学论坛网

  7月25日,《糖尿病护理》(Diabetes Care)杂志在线发表美国女性健康行动对糖尿病发生风险的研究结果。在绝经后女性中,尽管不同人种或种族糖尿病发生风险有一定差异,但是这种变异性可归因于不同人群的生活方式差异。大多数糖尿病史可以预防的,降低糖尿病风险的手段对所有人种或种族人群都同样有效。   研究对象是美国女性健康行动1993年-1998年招募,并随访至2009年的158833例绝经后

  7月25日,《糖尿病护理》(Diabetes Care)杂志在线发表美国女性健康行动对糖尿病发生风险的研究结果。在绝经后女性中,尽管不同人种或种族糖尿病发生风险有一定差异,但是这种变异性可归因于不同人群的生活方式差异。大多数糖尿病史可以预防的,降低糖尿病风险的手段对所有人种或种族人群都同样有效。
  研究对象是美国女性健康行动1993年-1998年招募,并随访至2009年的158833例绝经后女性,搜集这些人群种族或人种、基线糖尿病流行情况及糖尿病发病率数据。通过Cox比例危险比模型的危险比(HR)及95%CI,评估种族或人种与其他潜在危险因素以及糖尿病发生之间的关系。
  结果显示,基线时平均年龄为63岁,种族分布如下:非西班牙白人占84.1%,非西班牙黑人占9.2%,西班牙人占4.1% ,亚洲人占2.6%。经过平均10.4年随访及相关因素校正后,其他人种与白人相比的糖尿病发生风险HR分别为:黑人1.55(95% CI 1.47–1.63),西班牙人1.67(1.54–1.81),亚洲人1.86(1.68–2.06)。低风险因素(如体重、体育运动、饮食治疗和吸烟)的白人、黑人及西班牙人糖尿病发生风险分别为60%、69%和63%。尽管种族之间危险因素对糖尿病发生风险的影响有轻微差异,但是不同种族间的结果大体保持一致。体重正常且运动量最大的女性较肥胖和缺乏运动者糖尿病风险低1/3。

链接:Ma Y, Hébert JR, Manson JE, Balasubramanian R, Liu S, Lamonte MJ, Bird CE, Ockene JK, Qiao Y, Olendzki B, Schneider KL, Rosal MC, Sepavich DM, Wactawski-Wende J, Stefanick ML, Phillips LS, Ockene IS, Kaplan RC, Sarto GE, Garcia L, Howard BV.Determinants of Racial/Ethnic Disparities in Incidence of Diabetes in Postmenopausal Women in the U.S.Diabetes Care. 2012 Jul 25.
  


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