Am J Otolaryngol:60岁到75岁过敏性鼻炎患者中舌下免疫治疗效果和依从性分析

2020-06-10 AlexYang MedSci原创

最近,有研究人员评估了舌下免疫治疗(SLIT)在不小于60岁的屋尘螨(HDM)诱导的过敏性鼻炎患者中的效果和依从性情况。

最近,有研究人员评估了舌下免疫治疗(SLIT)在不小于60岁的屋尘螨(HDM)诱导的过敏性鼻炎患者中的效果和依从性情况。

研究包括了86名60-75岁的AR患者,以1:1的比例随机分配到对照组和治疗组。对照组进行标准的药物治疗,治疗组则使用SLIT治疗和药物治疗。研究发现,治疗组中25名(58.1%)患者和对照组中的20名(46.5%)完成了研究(P>0.05)。提前停止SLIT治疗的主要原因包括失去联系和症状减轻。同时,患者的CSMS和VAS在两个组中跟基线时间点以及基线时间点后任何时间点相比均显著减少(P<0.05)。CSMS和VAS在两组之间的表明存在统计学显著差异,且第24个月在SLIT组中具有优势(P<0.05),而在第6个月和第12个月没有差异(P>0.05)。

最后,研究人员指出,41.9%的患者在SLIT治疗2年内停止,主要原因是失去联系和症状减轻。他们的研究表明了SLIT联合药物治疗要比单独的药物治疗更好。

原始出处:

Hong Chen , Yong Chen ,Biyu Lin et al. Efficacy and Adherence of Sublingual Immunotherapy in Patients Aged 60 to 75 Years Old With House Dust Mite-Induced Allergic Rhinitis. Am J Otolaryngol. 8 May 2019.

 

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    2020-06-12 fyxzlh
  4. [GetPortalCommentsPageByObjectIdResponse(id=2047267, encodeId=fbca204e2673a, content=<a href='/topic/show?id=6f5294036b1' target=_blank style='color:#2F92EE;'>#过敏性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94036, encryptionId=6f5294036b1, topicName=过敏性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0a8e213, createdName=hongbochen, createdTime=Mon Jan 18 16:22:42 CST 2021, time=2021-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1894157, encodeId=a34d189415e55, content=<a href='/topic/show?id=5e456463eee' target=_blank style='color:#2F92EE;'>#治疗效果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64637, encryptionId=5e456463eee, topicName=治疗效果)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=373a131, createdName=jxrzshh, createdTime=Fri Sep 18 09:22:42 CST 2020, time=2020-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1319347, encodeId=399a131934edf, content=<a href='/topic/show?id=60172686668' target=_blank style='color:#2F92EE;'>#依从性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26866, encryptionId=60172686668, topicName=依从性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9df476, createdName=fyxzlh, createdTime=Fri Jun 12 04:22:42 CST 2020, time=2020-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1032531, encodeId=285610325315c, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Wed Jun 10 16:22:42 CST 2020, time=2020-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1047073, encodeId=e612104e07364, content=疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Wed Jun 10 16:22:42 CST 2020, time=2020-06-10, status=1, ipAttribution=)]
    2020-06-10 内科新手

    谢谢梅斯提供这么好的信息,学到很多

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2047267, encodeId=fbca204e2673a, content=<a href='/topic/show?id=6f5294036b1' target=_blank style='color:#2F92EE;'>#过敏性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94036, encryptionId=6f5294036b1, topicName=过敏性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0a8e213, createdName=hongbochen, createdTime=Mon Jan 18 16:22:42 CST 2021, time=2021-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1894157, encodeId=a34d189415e55, content=<a href='/topic/show?id=5e456463eee' target=_blank style='color:#2F92EE;'>#治疗效果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64637, encryptionId=5e456463eee, topicName=治疗效果)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=373a131, createdName=jxrzshh, createdTime=Fri Sep 18 09:22:42 CST 2020, time=2020-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1319347, encodeId=399a131934edf, content=<a href='/topic/show?id=60172686668' target=_blank style='color:#2F92EE;'>#依从性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26866, encryptionId=60172686668, topicName=依从性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9df476, createdName=fyxzlh, createdTime=Fri Jun 12 04:22:42 CST 2020, time=2020-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1032531, encodeId=285610325315c, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Wed Jun 10 16:22:42 CST 2020, time=2020-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1047073, encodeId=e612104e07364, content=疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Wed Jun 10 16:22:42 CST 2020, time=2020-06-10, status=1, ipAttribution=)]
    2020-06-10 CHANGE

    疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的

    0

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