ARD:类风湿关节炎患者心梗风险与糖尿病患者相当

2011-06-10 赵鑫 中国医学论坛报

  ■研究内容   丹麦学者研究发现,类风湿关节炎(RA)患者心梗(MI)风险与糖尿病(DM)患者及年长10岁的非RA人群相当。论文发表于即将出版的《风湿病年鉴》6月期 [Ann Rheum Dis, 2011, 70(6):929]。   研究纳入431万余名研究对象,包括10477例RA患者和130215例DM患者。   结果显示,MI的总发病率比(IRR)在RA患者与DM患者中均为1.

  ■研究内容   丹麦学者研究发现,类风湿关节炎(RA)患者心梗(MI)风险与糖尿病(DM)患者及年长10岁的非RA人群相当。论文发表于即将出版的《风湿病年鉴》6月期 [Ann Rheum Dis, 2011, 70(6):929]。   研究纳入431万余名研究对象,包括10477例RA患者和130215例DM患者。   结果显示,MI的总发病率比(IRR)在RA患者与DM患者中均为1.7。经性别和年龄分层分析表明,各亚组MI风险均显著升高,且年龄较低患者的风险比值比(RR)较高,尤其是年龄低于50岁的DM或RA女性患者(见图)。RA患者MI风险不受RA药物治疗时间影响,且与年长10岁的非RA人群的总MI风险相当。 {nextpage}   ■各方观点   研究者认为,该研究结论证实并拓宽了既往该领域的研究认知,对RA患者应进行更加积极的心血管疾病(CVD)一级预防。有必要进行关于RA患者CVD风险处理策略的前瞻性研究。   同期述评者荷兰阿姆斯特丹自由大学医学中心迈克尔(Michael)等提出,① RA患者的CVD风险已被大众所认知,但很多地区并未建立相应临床措施进行处理。② 要

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    2011-06-12 lmm397
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