J Indian Soc Periodontol:压力背景下慢性牙周炎患者血清和唾液活性氧代谢产物及皮质醇水平的变化

2018-03-03 MedSci MedSci原创

牙周病不是传统的细菌感染,而是由易感宿主中的一组微生物引起的免疫应答引发的炎症性疾病。既往许多研究探究了牙周炎的发病机制。目前慢性牙周炎的研究主要是针对各种危险因素、遗传因素和疾病进展之间的关系。 本研究旨在评估血清中皮质醇和活性氧代谢物(ROM)浓度,并找出它们在牙周健康和疾病中的关联。 研究共纳入30例患者,分为慢性牙周炎(I组)和应激性慢性牙周炎(II组)两组,并评估ROM与皮质醇水平之间的

牙周病不是传统的细菌感染,而是由易感宿主中的一组微生物引起的免疫应答引发的炎症性疾病。既往许多研究探究了牙周炎的发病机制。目前慢性牙周炎的研究主要是针对各种危险因素、遗传因素和疾病进展之间的关系。

本研究旨在评估血清中皮质醇和活性氧代谢物(ROM)浓度,并找出它们在牙周健康和疾病中的关联。

研究共纳入30例患者,分为慢性牙周炎(I组)和应激性慢性牙周炎(II组)两组,并评估ROM与皮质醇水平之间的相关性。该研究首次在血清和唾液中检查ROM和皮质醇的水平,以探究二者之间的关联。采用软件程序(SPSS 16),Pearson相关和配对t检验进行统计分析。

结果显示,组I和组II的平均ROM水平的比较显示组II中的平均ROM水平比组I高得多。

该结果表明,压力可以通过增加皮质醇和ROM水平在牙周疾病的进展中起作用。

原始出处:


Sudhakar U, Thyagarajan R, et al., Indagation of serum and salivary reactive oxygen metabolite and cortisol levels in chronic periodontitis and stress-induced chronic periodontitis patients. J Indian Soc Periodontol. 2017 Sep-Oct;21(5):371-375. doi: 10.4103/jisp.jisp_6_18.

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    2018-03-05 徐岩
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    2018-03-05 xiaogang319
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    2018-03-03 wqkm

    ^_^^_^^_^

    0