CPFI：HCV感染可促使颈动脉粥样硬化发生和发展

2015-01-28 MedSci MedSci原创

关于慢性丙型肝炎和颈动脉粥样硬化之间关系的研究产生的结果多种多样。基于之前有限的研究，我们通过进一步的探究，我们得出慢性丙型肝炎和颈动脉粥样硬化之间的关系。我们在PubMed和Scopus 中检索了所有发表的慢性丙型肝炎的诊断、颈动脉以及相关颈动脉硬化风险估计的研究，对筛选出来的文献进行质量评估，对其中符合条件进行后续叙述性和定量性合成方法。我们初始确定了190篇文章，通过初步审核缩小到1

关于慢性丙型肝炎和颈动脉粥样硬化之间关系的研究产生的结果多种多样。基于之前有限的研究，通过进一步的探究得出慢性丙型肝炎和颈动脉粥样硬化之间的关系。

我们在PubMed和Scopus 中检索了所有发表的慢性丙型肝炎的诊断、颈动脉以及相关颈动脉硬化风险估计的研究，对筛选出来的文献进行质量评估，对其中符合条件进行后续叙述性和定量性合成方法。

我们初始确定了190篇文章，通过初步审核缩小到16篇相关研究的文章。最后通过质量评估，有7项研究用于叙述性合成方法，有5项研究被用于后续Meta分析。在叙述性合成方中，其中的5项研究中患者通过B超检查显示双侧颈动脉内膜有增厚的风险，在5项研究中通过B超检查的患者被评定有颈动脉斑块形成的风险。在后续Meta分析中感染慢性丙型肝炎患者发展成颈动脉内膜的增厚的风险是未感染丙型肝炎患者的4.03倍。感染慢性丙型肝炎患者患颈动脉斑块形成的风险是未感染丙型肝炎患者的3.94倍。

现有证据表明，丙型肝炎病毒(HCV)或与丙肝病毒感染相关的因素可能促使颈动脉粥样硬化的发生和发展。

原始出处

Olubamwo OO1, Onyeka IN, Miettola J, Kauhanen J, Tuomainen TP.Hepatitis C as a risk factor for carotid atherosclerosis - a systematic review.Clin Physiol Funct Imaging. 2015 Jan 26

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2015-08-07 huangshifeng

#粥样硬化#

24 0
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2015-10-18 mhzhuang@stu.e

#颈动脉#

26 0
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2015-01-30 ymljack

#HCV#

24 0
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2015-01-30 经常头晕

#颈动脉粥样硬化#

25 0
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2015-01-30 12498e5fm18(暂无昵称)

#HCV感染#

23 0
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2015-01-28 223.104.5.**

交叉学科。HlV感染也一样

124 0
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2015-01-28 223.104.5.**

HBV暂不确定

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CPFI：HCV感染可促使颈动脉粥样硬化发生和发展

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CPFI：HCV感染可促使颈动脉粥样硬化发生和发展

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