Science:人类胚胎发育免费在线互动式3D图集建成

2016-12-29 生物探索 生物探索

导读 11月25日的Science上的一篇论文报道了荷兰的研究人员创造了一个更新的互动式3D图集,描绘了人类从受孕到两个月发育的各个阶段。这个图集对医学教科书上那些过时和错误的胚胎发育图片进行了纠正,对公众免费开放。在荷兰阿姆斯特丹的学术医疗中心的一组研究人员创造了一个更新的互动式3D图集,描绘了人类从受孕到两个月发育的各个阶段。他们的论文发表在11月25日的Science上,研究人员列出了医学文

导读 11月25日的Science上的一篇论文报道了荷兰的研究人员创造了一个更新的互动式3D图集,描绘了人类从受孕到两个月发育的各个阶段。这个图集对医学教科书上那些过时和错误的胚胎发育图片进行了纠正,对公众免费开放。

在荷兰阿姆斯特丹的学术医疗中心的一组研究人员创造了一个更新的互动式3D图集,描绘了人类从受孕到两个月发育的各个阶段。他们的论文发表在11月25日的Science上,研究人员列出了医学文本过时的原因,他们如何解决这个问题,新的3D图集的特点以及它可能对未来的医疗研究工作意味着什么。

在他们的论文中,研究人员指出,现代医学教科书所提供的受孕第一月的医学图像,是非常过时的。那是些半个世纪前或更长的时间所做的图片和图表。有些是1900年代早期的一些插图,甚至是由艺术家尝试把如小鼠等其他动物可以看到的早期发育,应在到人类的发育上。这个不幸的状态是由于对人类发育研究的限制,无论是那些仍然是活着的和正在生长的,包括那些已经死亡的。


为了提供研究人员和医生一个更好的参考工具,研究人员从Carnegie Collection收集的胚胎图像中扫描了约15000幅图,并用它们创造了一个更新的3D图集。工作涉及了分析这些图像,并通过比较它们而得出对如器官大小和位置的元素出现在多个具有里程碑意义发展日期过程中的共性图。

其结果是一个类似ZygoteBody(一个谷歌开发的人体浏览器)的虚拟图集。用户可以选择一个阶段,这表示了受孕后的天数,然后通过放大来操作图像以适应他们的需要,用来比较胚胎和成年人的手的大小,或者是分离图层查看器官、神经系统或是循环系统的图。这个重建的3D图集 (http://3datlasofhumanembryology.com) 是免费对公众开放的。


左边是孕9.5周人类胚胎皮肤图层,右边是所有重建的器官图层。

研究人员报告说他们的工作纠正了目前一些教科书上画错地方的器官以及在错误的时间点下的发育状况。他们声称这个新的图集对于研究人员更好地了解特别是那些很早就开始的出生缺陷是很有帮助的。它也为医生提供关于在孕妇中胚胎发育的信息。

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    2016-12-31 ailian1202
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    2016-12-31 zhaojie88
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    2016-12-31 jichang