Adv Clin Exp Med:激光治疗后抗生素治疗牙周炎的效果

2018-08-04 MedSci MedSci原创

牙周治疗中的激光技术可以帮助减少细菌总数。本研究旨在评估使用掺铒钇铝石榴石激光(Er:YAG激光- ERL),刮治和根面平整(SRP)与光动力疗法(PDT)或单独SRP的牙周袋清创效果。此外,还评估了牙齿活力和软组织碳化。研究纳入了84名患者,包括1169颗单根牙齿,分为3组(n = 28)。G1组的ERL为40mJ,频率为40Hz,通量为63.66 J/cm2。G2组为SRP + PDT(635

牙周治疗中的激光技术可以帮助减少细菌总数。本研究旨在评估使用掺铒钇铝石榴石激光(Er:YAG激光- ERL),刮治和根面平整(SRP)与光动力疗法(PDT)或单独SRP的牙周袋清创效果。此外,还评估了牙齿活力和软组织碳化。

研究纳入了84名患者,包括1169颗单根牙齿,分为3组(n = 28)。G1组的ERL为40mJ,频率为40Hz,通量为63.66 J/cm2。G2组为SRP + PDT(635nm二极管激光,12J能量和30s的照射时间)和甲苯胺蓝光敏剂(PS)(施加时间为60s)。G3组仅单独使用SRP。在42名受试者(G1:n = 11,G2:n = 14和G3:n = 17)中,有大量的伴放线聚集杆菌(Aa),牙龈卟啉单胞菌(Pg),密螺旋体(Td)和福赛斯坦纳菌(Tf),在治疗后3个月辅助使用克林霉素或阿莫西林+克拉维酸进行1周的抗生素治疗,剂量分别为600毫克/天或1000毫克/天。在基线和3个月,1周,6个月的随访时进行探诊深度(PD),牙龈退缩(RC),斑块指数(PI),探诊出血(BOP)和附着丧失(AT)的微生物学和临床分析。

结果显示,G1组斑块指数下降(p <0.05),且3个月后G1较G2下降的多(p <0.05)。与G2或G3相比,3个月和1周后G1中BOP的降低更高(p <0.02)。所有组的探诊深度均下降(p <0.05)。我们发现3个月后部分牙位的某些细菌减少,如中间普氏菌(Pi)(G1和G2),牙龈二氧化碳噬纤维菌(Cg)和核杆菌(En)(G3),6个月后En,Td,Tf(G1,G2和G3),Pi(G1和G2),Aa,微球菌(Pm)和Cg(G3),以及Pi(G1和G2),Tf(G2),Pg, En(G2和G3)和Pm(G3)(p <0.05)减少。我们没有观察到碳化或牙齿损伤的迹象。

综上所述,该研究结果表明,刮治和根面平整+ PDT和ERL可能是慢性牙周炎的一种 替代疗法。

原始出处:

Grzech-Leśniak K, Matys J, Dominiak M. Comparison of the clinical and microbiological effects of antibiotic therapy in periodontal pockets following laser treatment: An in vivo study. Adv Clin Exp Med. 2018 Jul 26. doi: 10.17219/acem/70413.

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    2019-05-10 hyf028
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    2018-08-06 oliver169
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    2018-08-04 CHANGE

    疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的

    0