J Gastroen Hepatol:香港炎症性肠病患者医疗支出及影响因素研究

2018-01-01 zhangfan MedSci原创

研究发现,对于新确诊炎症性肠病的患者,住院以及氨基水杨酸治疗费用占总医疗支出的56%,发病第一年的医疗花费最大,手术以及低血红蛋白会导致患者医疗支出显著上升

目前关于亚洲地区医疗保险利用的相关研究很少,近年来亚洲炎症性肠病(IBD)的发病率正在迅速上升。近日研究人员考察了香港地区IBD患者2年的医疗保险支出情况,并分析了相关高花费影响因素。

本次研究是对新确诊IBD患者的回顾性队列研究,记录IBD诊断后2年内患者的临床信息、住院记录、检查和IBD治疗花费。

435名新发IBD患者参与,其中克罗恩病198人,溃疡性结肠炎237人。所有患者2年内总直接医疗费用为$7072710,其中住院费占33%,5-氨基水杨酸治疗费用占23%,影像及内镜检查费用占17%,门诊花费占10%,手术占8%,生物制剂占6%。克罗恩病患者的直接医疗花费高于溃疡性结肠炎患者($9918vs $6634)。第二年后患者的直接医疗花费显著下降。手术(OR 7.1, 95% CI 2.9–17.2)以及低血红蛋白(OR 0.83, 95% CI 0.70–0.96)是导致高花费的重要因素。

研究发现,对于新确诊炎症性肠病的患者,住院以及氨基水杨酸治疗费用占总医疗支出的56%,发病第一年的医疗花费最大,手术以及低血红蛋白会导致患者医疗支出显著上升。

原始出处:


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    2018-08-12 许安
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time=2018-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274459, encodeId=80112e44598d, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Mon Jan 01 11:08:38 CST 2018, time=2018-01-01, status=1, ipAttribution=)]
    2018-01-04 大爰

    学习并分享!!

    0

  5. 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time=2018-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274459, encodeId=80112e44598d, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Mon Jan 01 11:08:38 CST 2018, time=2018-01-01, status=1, ipAttribution=)]
    2018-01-03 gwc384
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    2018-01-01 131****1460

    学习了受益匪浅

    0

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    2018-01-01 明月清辉

    谢谢分享.学习了

    0

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研究认为,炎症性肠病患者抑郁症状会导致患者治疗后疾病复发风险增加

Nat Commun:寄生虫中发现的蛋白质带来炎症性肠病新疗法

蠕虫寄生虫中的一种蛋白质有望带来炎症性肠道疾病的全新治疗方案,这种蛋白质可以避免目前免疫抑制剂药物带来的严重副作用。研究结果发表在《自然通讯》杂志上,这项研究表明,一种独特全新蠕虫蛋白,模仿人体中发现的一种细胞因子,称为转化生长因子β。

Am J Gastroenterol:炎症性肠病治疗方案的辅助决策

生物疗法的用药决策是高度个体化的,人口统计学和疾病特征对治疗决策的影响十分有限,每一个炎症性肠病患者的特征均十分显著,难以进行统计分类

2017 AOCC/APAGE共识:接受抗肿瘤坏死因子治疗的炎症性肠病患者结核感染的风险管理

2017年10月,亚洲克罗恩病和结肠炎组织(AOCC)联合亚太地区胃肠病学协会(APAGE)共同发布了接受抗肿瘤坏死因子治疗的炎症性肠病患者结核感染的风险评估和管理共识。文章主要建议内容包接受抗肿瘤坏死因子治疗括结核感染的风险,开始抗肿瘤坏死因子治疗前潜伏或活动性结核病筛查,准备抗肿瘤坏死因子治疗晚期结核感染的管理,抗肿瘤坏死因子治疗期间监测,抗肿瘤坏死因子治疗后结核感染的管理。

Frontiers in Immunology:吸烟可能导致炎症性肠病

一项新的研究首次表明了香烟烟雾对肠道炎症的直接影响。韩国的研究人员报告说,将老鼠暴露在香烟烟雾中会导致结肠炎,这是一种类似于克罗恩病的结肠炎症,并确定了一种特定的白细胞和炎症蛋白。这项研究今天发表在开放获取期刊《Frontiers in Immunology》杂志上,可以帮助科学家开发新的治疗炎症性肠病的方法,如克罗恩病,并提高吸烟者对结肠炎风险的认识。之前的研究表明,吸烟会显着增加克罗恩病的风险