SCI REP:冠心病筛查中餐后血糖由于空腹血糖和糖化血红蛋白!

2017-10-27 xing.T MedSci原创

在中国人群中,冠心病的严重程度与血糖有关,而不是胰岛素抵抗。PBG与冠心病的存在和严重程度呈正相关。

近日,Scientific reports 杂志上发表了一篇研究文章,研究人员的目的是评估空腹血糖(FBG)、餐后血糖(PBG)和糖化血红蛋白(HbA1c)在冠状动脉造影患者中的筛查价值。

研究人员基于受试者的FBG、PBG和HbA1c水平将连续就诊的1852例按计划进行冠状动脉造影的患者分为糖耐量正常(NGT)、糖调节受损(IGR)和糖尿病。研究人员将Gensini评分与糖代谢及胰岛素抵抗之间的相关性分析,并且采用多元线性回归和logistic回归分析分别对血糖变量和Gensini评分或冠心病之间的相关性进行分析。

在NGT、IGR和糖尿病的患者中分别有488例、622例和414例患者被诊断为冠心病。研究人员发现Gensini评分与FBG(r=0.09,P<0.01)、PBG(r=0.20,P<0.01)、糖化血红蛋白(r=0.19,P<0.01)呈正相关。而Gensini评分与空腹胰岛素(r=0.081,P=0.36)、餐后胰岛素(r=-0.02,P=0.61)或HOMAIR(r=-0.0059,P=0.13)无明显相关性。当将FBG、PBG和HbA1c汇集分析,只有PBG仍与Gensini评分以及冠心病的患病率相关。

在中国人群中,冠心病的严重程度与血糖有关,而不是胰岛素抵抗。PBG与冠心病的存在和严重程度呈正相关。

原始出处:

Jingjing Jiang,et al. Postprandial Blood Glucose Outweighs Fasting Blood Glucose and HbA1c in screening Coronary Heart Disease.Scientific reports. 2017. https://www.nature.com/articles/s41598-017-14152-y

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  1. [GetPortalCommentsPageByObjectIdResponse(id=299840, encodeId=266929984056, content=写的很好的文章.已看过, beContent=null, objectType=article, channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ad01994393, createdName=溜溜梅不酸, createdTime=Mon Mar 26 10:21:15 CST 2018, time=2018-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257758, encodeId=eaec25e758b1, content=学习了谢谢分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Wed Nov 01 10:03:29 CST 2017, time=2017-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1304963, encodeId=a1b013049630d, content=<a href='/topic/show?id=1970e539018' target=_blank style='color:#2F92EE;'>#空腹血糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75390, encryptionId=1970e539018, topicName=空腹血糖)], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160723/IMG57937A3BB59F33185.jpg, createdBy=7642322, createdName=手留余香, createdTime=Sun Oct 29 10:42:00 CST 2017, time=2017-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1488456, encodeId=6f8e1488456d6, content=<a href='/topic/show?id=019e1011e589' target=_blank style='color:#2F92EE;'>#餐后血糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101175, encryptionId=019e1011e589, topicName=餐后血糖)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76df8418429, createdName=gjsgj, createdTime=Sun Oct 29 10:42:00 CST 2017, time=2017-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=256457, encodeId=b71a25645ea6, content=谢谢.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ad4c106013, createdName=Drhzm308, createdTime=Fri Oct 27 20:15:30 CST 2017, time=2017-10-27, status=1, ipAttribution=)]
    2018-03-26 溜溜梅不酸

    写的很好的文章.已看过

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=299840, encodeId=266929984056, content=写的很好的文章.已看过, beContent=null, objectType=article, channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ad01994393, createdName=溜溜梅不酸, createdTime=Mon Mar 26 10:21:15 CST 2018, time=2018-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257758, encodeId=eaec25e758b1, content=学习了谢谢分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Wed Nov 01 10:03:29 CST 2017, time=2017-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1304963, encodeId=a1b013049630d, content=<a href='/topic/show?id=1970e539018' target=_blank style='color:#2F92EE;'>#空腹血糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75390, encryptionId=1970e539018, topicName=空腹血糖)], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160723/IMG57937A3BB59F33185.jpg, createdBy=7642322, createdName=手留余香, createdTime=Sun Oct 29 10:42:00 CST 2017, time=2017-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1488456, encodeId=6f8e1488456d6, content=<a href='/topic/show?id=019e1011e589' target=_blank style='color:#2F92EE;'>#餐后血糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101175, encryptionId=019e1011e589, topicName=餐后血糖)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76df8418429, createdName=gjsgj, createdTime=Sun Oct 29 10:42:00 CST 2017, time=2017-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=256457, encodeId=b71a25645ea6, content=谢谢.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ad4c106013, createdName=Drhzm308, createdTime=Fri Oct 27 20:15:30 CST 2017, time=2017-10-27, status=1, ipAttribution=)]
    2017-11-01 大爰

    学习了谢谢分享!!

    0

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  4. [GetPortalCommentsPageByObjectIdResponse(id=299840, encodeId=266929984056, content=写的很好的文章.已看过, beContent=null, objectType=article, channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ad01994393, createdName=溜溜梅不酸, createdTime=Mon Mar 26 10:21:15 CST 2018, time=2018-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257758, encodeId=eaec25e758b1, content=学习了谢谢分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Wed Nov 01 10:03:29 CST 2017, time=2017-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1304963, encodeId=a1b013049630d, content=<a href='/topic/show?id=1970e539018' target=_blank style='color:#2F92EE;'>#空腹血糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75390, encryptionId=1970e539018, topicName=空腹血糖)], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160723/IMG57937A3BB59F33185.jpg, createdBy=7642322, createdName=手留余香, createdTime=Sun Oct 29 10:42:00 CST 2017, time=2017-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1488456, encodeId=6f8e1488456d6, content=<a href='/topic/show?id=019e1011e589' target=_blank style='color:#2F92EE;'>#餐后血糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101175, encryptionId=019e1011e589, topicName=餐后血糖)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76df8418429, createdName=gjsgj, createdTime=Sun Oct 29 10:42:00 CST 2017, time=2017-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=256457, encodeId=b71a25645ea6, content=谢谢.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ad4c106013, createdName=Drhzm308, createdTime=Fri Oct 27 20:15:30 CST 2017, time=2017-10-27, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=299840, encodeId=266929984056, content=写的很好的文章.已看过, beContent=null, objectType=article, channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ad01994393, createdName=溜溜梅不酸, createdTime=Mon Mar 26 10:21:15 CST 2018, time=2018-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257758, encodeId=eaec25e758b1, content=学习了谢谢分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Wed Nov 01 10:03:29 CST 2017, time=2017-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1304963, encodeId=a1b013049630d, content=<a href='/topic/show?id=1970e539018' target=_blank style='color:#2F92EE;'>#空腹血糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75390, encryptionId=1970e539018, topicName=空腹血糖)], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160723/IMG57937A3BB59F33185.jpg, createdBy=7642322, createdName=手留余香, createdTime=Sun Oct 29 10:42:00 CST 2017, time=2017-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1488456, encodeId=6f8e1488456d6, content=<a href='/topic/show?id=019e1011e589' target=_blank style='color:#2F92EE;'>#餐后血糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101175, encryptionId=019e1011e589, topicName=餐后血糖)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76df8418429, createdName=gjsgj, createdTime=Sun Oct 29 10:42:00 CST 2017, time=2017-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=256457, encodeId=b71a25645ea6, content=谢谢.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ad4c106013, createdName=Drhzm308, createdTime=Fri Oct 27 20:15:30 CST 2017, time=2017-10-27, status=1, ipAttribution=)]
    2017-10-27 Drhzm308

    谢谢.学习了

    0

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