Lancet Diab & Endo:超负荷工作易患糖尿病

2014-09-28 马宏伟 译 医学论坛网

据目前为止该领域最大的一项研究显示,每周工作超过55小时体力劳动或其他低社会经济地位的工作的人群患2型糖尿病的风险增加30%,该结果已发表在《柳叶刀--糖尿病与内分泌学》杂志上。 英国伦敦大学流行病学教授Mika Kivimaki及其同事研究了长工作时间对2型糖尿病影响,对截至2014年4月30日为止公开发表的研究和未发表的个人数据进行了系统回顾和荟萃分析。 数据分析来自4篇发表的研究与19项

据目前为止该领域最大的一项研究显示,每周工作超过55小时体力劳动或其他低社会经济地位的工作的人群患2型糖尿病的风险增加30%,该结果已发表在《柳叶刀--糖尿病与内分泌学》杂志上。

英国伦敦大学流行病学教授Mika Kivimaki及其同事研究了长工作时间对2型糖尿病影响,对截至2014年4月30日为止公开发表的研究和未发表的个人数据进行了系统回顾和荟萃分析。

数据分析来自4篇发表的研究与19项未发表的数据,包括来自美国、欧洲、日本和澳大利亚的222例男性和120名女性,平均随访7.6年,结果发现,每周工作超过55小时和正常投入一周35 - 40小时工作的人群相比,患2型糖尿病的风险相似。然而,当研究人员仔细研究时,注意到结果有显著差异。

进一步的分析显示,每周工作超过55小时、做低社会经济地位工作的个体,和每周工作35到40小时的人群相比,患糖尿病的相关风险增加约30%。即使考虑到健康习惯,如吸烟和体育活动,以及其他危险因素包括年龄、性别、和肥胖,结果亦然。即使已被证明能增加肥胖和2型糖尿病风险的轮班工作因素之外,这种相关依然显著。

研究人员说,还需要进一步研究来确定做低社会经济地位工作人群的长时间工作和糖尿病之间的潜在关联机制,但是提出了一些可能的解释,包括混乱的工作时间表,几乎没有时间参加健康恢复行为如睡觉、放松和锻炼。

据Kivimaki教授说,就该问题所有可用的池研究令我们调查工作时间和糖尿病风险之间关联比之前更精确。尽管长时间工作不太可能增加每个人的糖尿病风险,卫生专业人员应该意识到,做低社会经济地位工作的人们患糖尿病风险显著增加。

在随后的评论中,美国宾夕法尼亚州立大学的Orfeu Buxton博士、以及哈佛大学公共卫生学院的Cassandra Okechukwu博士写道,Kivimaki及其同事的优雅设计研究对糖尿病风险的流行病学和干预研究提供了坚实基础。甚至在控制肥胖和体育活动(通常糖尿病风险防范的重点)之后,结果相关依然显著。这表明,影响健康状况的工作因素和压力可能需要被列入糖尿病预防的一部分。

原始出处:


Prof Mika Kivimäki PhD a b Corresponding AuthorEmail Address, Prof Marianna Virtanen PhD c, Prof Ichiro Kawachi MD d, Solja T Nyberg MSc c, Prof Lars Alfredsson PhD e f, G David Batty PhD a g h, Prof Jakob B Bjorner MD i, Marianne Borritz MD j, Prof Eric J Brunner PhD a, Hermann Burr PhD k, Prof Nico Dragano PhD l, Jane E Ferrie PhD a m, Eleonor I Fransson PhD f n o, Mark Hamer PhD a, Katriina Heikkilä PhD c p, Prof Anders Knutsson PhD q, Prof Markku Koskenvuo MD r, Ida E H Madsen PhD i, Martin L Nielsen MD j, Maria Nordin PhD s, Tuula Oksanen PhD c, Jan H Pejtersen PhD t, Jaana Pentti PhD c, Prof Reiner Rugulies PhD i u, Paula Salo PhD c v, Prof Johannes Siegrist PhD l, Andrew Steptoe PhD a, Prof Sakari Suominen MD w x y, Prof Töres Theorell MD o, Prof Jussi Vahtera MD c y z, Prof Peter J M Westerholm MD aa, Prof Hugo Westerlund PhD o, Archana Singh-Manoux PhD a ab, Markus Jokela PhD ac.Long working hours, socioeconomic status, and the risk of incident type 2 diabetes: a meta-analysis of published and unpublished data from 222 120 individuals.The Lancet Diabetes & Endocrinology, Early Online Publication, 25 September 2014
doi:10.1016/S2213-8587(14)70178-0


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    2015-06-05 ljjj1053

    好好学习学习

    0

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    2015-04-11 x35042875

    控制好糖尿病可能提高肝硬化患者的预后。

    0

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    2015-02-20 howi
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