Obstet Gynecol:分娩过程中胎儿并发症的预测

2014-08-21 佚名 中国妇产科网

大多数分娩过程中的胎儿缺氧发生于无妊娠合并症的产妇,而现有的产程监测技术并不能减少足月新生儿脑瘫的发生。这篇文章以此为背景提出风险评分,对正常妊娠分娩前实施风险分层评估预测。对601名研究对象采用前瞻性观察研究,在分娩发动前对所有研究对象行超声检查,测量胎儿多普勒血流阻力指数,记录脐动脉、脐静脉和大脑中动脉搏动指数,形成风险评分系统,分析其和分娩结局的相关性。研究初步得出的结论是:正常脐动脉搏动指

大多数分娩过程中的胎儿缺氧发生于无妊娠合并症的产妇,而现有的产程监测技术并不能减少足月新生儿脑瘫的发生。这篇文章以此为背景提出风险评分,对正常妊娠分娩前实施风险分层评估预测。对601名研究对象采用前瞻性观察研究,在分娩发动前对所有研究对象行超声检查,测量胎儿多普勒血流阻力指数,记录脐动脉、脐静脉和大脑中动脉搏动指数,形成风险评分系统,分析其和分娩结局的相关性。

研究初步得出的结论是:正常脐动脉搏动指数的均值是0.80(范围0.46-1.53),第10百分位数是0.64,第90 百分位数是0.89.正常大脑中动脉搏动指数是1.37(范围0.68-2.32),第10百分位数是1.04,第90百分位数是1.71.大脑中动脉与脐动脉搏动指数的平均比值是1.77(范围0.56-3.15),第10百分位数是,1.26,第90百分位数是2.32.脐静脉平均流速是60.4 ml/min/Kg。第10百分位数是41.6 ml/min/Kg,第90百分位数是79.1 ml/min/Kg.依据第10百分位数、平均值、第90 百分位数分别对大脑中动脉搏动指数、脐动脉搏动指数、大脑中动脉与脐动脉搏动指数比值、脐静脉平均流速进行0、1、2三级量化评分,每位研究对象可得到4项测量指标的累积量化评分,分值(0-8分)。分析妊娠结局及围产儿结局与评分的相关性,结果显示,7-8分的胎儿急诊剖宫产分娩率显著增高,为53.3%,相比之下,0-2分的胎儿急诊剖宫产分娩率仅为3.4%;且7-8分的围产儿心电监护病理性异常显著增加。

点评:本研究的意义在于多普勒血流指数量化评分联合胎儿心电监护可提高分娩时胎儿缺氧的预测程度。

原始出处:

Prior T1, Mullins E, Bennett P, Kumar S.Prediction of fetal compromise in labor.Obstet Gynecol. 2014 Jun;123(6):1263-71. doi: 10.1097/AOG.0000000000000292.


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    2015-02-02 yhy100200
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    2015-06-13 丁鹏鹏
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    2014-08-23 linlin2312