BMJ:Meta分析显示n-3多不饱和脂肪酸可以预防乳腺癌

2013-07-01 佚名 医学界

  根据来自亚洲和欧洲的26项研究的荟萃分析表明,n-3多不饱和脂肪酸(多不饱和脂肪酸)消费水平较高的国家与较低的消费水平国家相比可以降低14%患乳腺癌的风险。鱼类(特别是鲑鱼,金枪鱼和沙丁鱼)是海洋中n-3多不饱和脂肪酸最丰富的来源。作者指出,本研究中鱼油的补充也考虑这些含有脂肪酸的饮食来源。   值得注意的是,观察鱼的整体摄入量和乳腺癌之间没有显著关联。   这项在线发表在BMJ的研究中,

  根据来自亚洲和欧洲的26项研究的荟萃分析表明,n-3多不饱和脂肪酸(多不饱和脂肪酸)消费水平较高的国家与较低的消费水平国家相比可以降低14%患乳腺癌的风险。鱼类(特别是鲑鱼,金枪鱼和沙丁鱼)是海洋中n-3多不饱和脂肪酸最丰富的来源。作者指出,本研究中鱼油的补充也考虑这些含有脂肪酸的饮食来源。
   值得注意的是,观察鱼的整体摄入量和乳腺癌之间没有显著关联。
   这项在线发表在BMJ的研究中,研究人员引用各种实验室研究结果意图说明,食物中的n-3多不饱和脂肪酸是脂肪中最有前途的亚型,可以抑制或减少疾病发生的风险。上一项关于n-3多不饱和脂肪酸和乳腺癌的研究鱼龙混杂。在这篇前瞻性研究中,作者写道,鱼是海洋的n-3多不饱和脂肪酸最丰富的来源,显示出降低疾病的风险。
   研究小组表示,这可能是第一次将可用的前瞻性队列研究汇总,总结饮食中摄取鱼类和N-3多不饱和脂肪酸与乳腺癌发生之间的关联。他们发现,海洋中的n-3多不饱和脂肪酸可以使得患乳腺癌的风险降低14%(相对风险[RR]为最高与最低摄入量0.86)。亚组分析表明,经常食用海洋的n-3多不饱和脂肪酸是有帮助的。增食海洋n-3多不饱和脂肪酸0.1克/天可以使得患乳腺癌的风险减少了5%。这种风险的减少可以通过每周吃鱼1或2份来实现。
  值得注意的是,食用包含在一些坚果和植物油中的α-亚麻酸(ALA)与疾病发生的风险的减少没有显著关联。ALA是n-3多不饱和脂肪酸 的一种类型。
   研究人员提供了对于食用海洋n-3多不饱和脂肪酸减少疾病风险的大量的解释。研究人员认为,海洋的n-3多不饱和脂肪可能会酸降低雌激素的生产,从而降低雌激素刺激细胞的生长的作用。   

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    2013-12-31 一闲
  3. 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  4. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579939, encodeId=ec2f15e9939f5, content=<a href='/topic/show?id=65f0101268d6' target=_blank style='color:#2F92EE;'>#饱和脂肪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101268, encryptionId=65f0101268d6, topicName=饱和脂肪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b0db16571375, createdName=斯嘉莉, createdTime=Wed Jul 03 13:08:00 CST 2013, time=2013-07-03, status=1, ipAttribution=)]
    2013-12-02 guojianrong
  5. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579939, encodeId=ec2f15e9939f5, content=<a href='/topic/show?id=65f0101268d6' target=_blank style='color:#2F92EE;'>#饱和脂肪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101268, encryptionId=65f0101268d6, topicName=饱和脂肪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b0db16571375, createdName=斯嘉莉, createdTime=Wed Jul 03 13:08:00 CST 2013, time=2013-07-03, status=1, ipAttribution=)]
    2014-01-11 gaoxiaoe
  6. 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  7. 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     ω-3脂肪酸类预防术后房颤(OPERA)和ω-3鱼油延迟房颤复发(FORWARD)研究均表明,心脏手术患者短期应用鱼油制剂未能降低术后心房颤动(AF)发生率,并且鱼油制剂亦不能预防房颤复发。研究结果于美国心脏学会(AHA)2012科学年会公布。   OPERA研究:鱼油对预防术后房颤发生无效   双盲、安慰剂对照、随机OPERA研究共纳入1516例计划行心脏手术的患者。患者主要排除

AHA2012:鱼油并未减少心脏术后AF发生

一项研究显示,心脏手术病人短期使用鱼油未能减少术后心房纤维性颤动(AF)的发生率。意太利RobertoMarchioli博士今日在此于美国心脏协会(AHA)2012年学术会议上提交其最新的临床试验所见结果。他解释说术后AF很常见,累及30%心外科手术后极其衰弱的病人。 在该项命名为“Omega-3脂肪酸用于预防手术后心房纤维性颤动(OPERA)”的研究中,积极治疗组和安慰剂组在预防术后AF上未见

NEJM:Omega-3鱼油不能预防心血管疾病

日前,一项大型研究结果显示,富含Omega-3脂肪酸的鱼油补充剂,对心血管疾病高风险患者可能并没有帮助。该报告发表在了5月9日出版的《新英格兰医学杂志》(New England Journal of Medicine)上。在2010年,意大利的研究人员开展了这项研究,他们把12513名病人分成两组,一组服用Omega-3补充剂,另一组服用橄榄油安慰剂。以前的临床试验表明,对于心血管疾病患者或曾经历

JAMA:鱼油或能延长移植物畅通时间

近日,刊登在《美国医学会杂志》(JAMA)上的一项新研究披露,在血管通路中使用新型合成型动静脉移植物(一种嫁接在动静脉之间的合成物管子)的血液透析患者,每日摄取鱼油,12个月内对移植物通畅性丧失比例有一定影响,但是该比例不会显著降低。鱼油是鱼体内的全部油类物质的统称,它包括体油、肝油和脑油。 研究报告指出:“理想的血液透析需要可靠的血管通路,包括动静脉瘘(用手术方法在动脉与静脉间创建一种连接)、