DIABETES CARE:食物供应不稳定增加DM患者代谢紊乱风险

2013-07-01 完美事业 DXY

为了确定食物供应不稳定是否与糖尿病患者血糖、胆固醇和血压控制恶化相关。来自波士顿马萨诸塞州总医院医学系普通内科的Berkowitz博士等人进行了一项研究,研究发现,食物供应不稳定与糖尿病患者不良代谢控制显著相关。研究结果在线发表于2013年6月11日的美国《糖尿病治疗》(Diabetes Care)杂志上。 研究人员对1999-2008年开展的“全国健康和营养调查研究”的参与者的数据进行横断面分

为了确定食物供应不稳定是否与糖尿病患者血糖、胆固醇和血压控制恶化相关。来自波士顿马萨诸塞州总医院医学系普通内科的Berkowitz博士等人进行了一项研究,研究发现,食物供应不稳定与糖尿病患者不良代谢控制显著相关。研究结果在线发表于2013年6月11日的美国《糖尿病治疗》(Diabetes Care)杂志上。
研究人员对1999-2008年开展的“全国健康和营养调查研究”的参与者的数据进行横断面分析。纳入所有自我报告有糖尿病(1型或2型)或使用糖尿病药物的成人数据。食物供应不稳定采用成人食物保障调查模块测定。所关注的结果表示为HbA1c >9.0%(75 mmol/mol),LDL-胆固醇>100 mg/dL,收缩压>140 mmHg或舒张压>90 mmHg的患者比例。采用多变量logistic回归法对结果进行分析。
结果显示,在所研究的2,557名糖尿病患者中,HbA1c >9.0% (75 mmol/mol)的患者中食物供应不稳定的成人所占比例较高(27.0 vs. 13.3%, P<0.001)。经年龄、性别、教育程度、家庭收入、保险情况和类型、吸烟情况、BMI、糖尿病病程、使用的糖尿病药物和类型以及平常的护理来源校正后,食物供应不稳定与不良血糖控制仍显著相关(比值比[OR] 1.53[95% CI 1.07-2.19])。经上述变量校正前后,食物供应不稳定也与不良LDL控制相关(患者比例为68.8 vs. 49.8%,P<0.002;OR 1.86[1.01-3.44])。食物供应不稳定与血压控制无关。
研究发现,食物供应不稳定与糖尿病患者不良代谢控制显著相关。采取一定的干预措施解决食物保障以及临床因素以成功处理易感人群的慢性疾病是必须的。

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    2013-07-03 yhy100201

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