中晟全肽宣布完成A轮融资1亿元,打造全球多肽药物研发新引擎

2019-07-26 佚名 美通社

7月26日,湖南中晟全肽生化有限公司(以下简称“中晟全肽”)宣布完成1亿元人民币A轮融资,由天士力资本旗下渤溢基金领投,兴湘新兴产业基金等跟投。本轮融资将主要用于多肽库构建、多肽新药筛选平台优化及自主研发新药的开发。中晟全肽成立于2017年,是一家拥有国际化水平的创新能力以及临床前多肽新药研发和产业化实力,聚焦超大容量多肽库研发、生产、销售及多肽新药筛选研发技术服务的公司,致力于打造全球多肽药物研

7月26日,湖南中晟全肽生化有限公司(以下简称“中晟全肽”)宣布完成1亿元人民币A轮融资,由天士力资本旗下渤溢基金领投,兴湘新兴产业基金等跟投。本轮融资将主要用于多肽库构建、多肽新药筛选平台优化及自主研发新药的开发。




中晟全肽成立于2017年,是一家拥有国际化水平的创新能力以及临床前多肽新药研发和产业化实力,聚焦超大容量多肽库研发、生产、销售及多肽新药筛选研发技术服务的公司,致力于打造全球多肽药物研发新引擎。

中晟全肽是由蛋白质研究和合成生物学领域专家王珠银博士、湖南省“百人计划”***李向群博士以及专注高科技领域投资的陈磊先生于共同创建 。谈到此次融资,中晟全肽联合创始人、CSO王珠银博士表示,“我们很荣幸吸引了大量投资人的关注,感谢渤溢基金等知名投资机构对中晟全肽多肽新药研发产业化和公司发展势头的高度认可。渤溢基金也是国内某 “巨型新药种子库(小分子)”企业A轮投资方,围绕创新药研发的上下游进行了广泛的投资、布局,本轮融资也将进一步助推中晟全肽扩大多肽库的规模和提升技术,以及推进自主研发新药的临床开发、加速国际市场开发”。



相较小分子药物及大分子药物,多肽类药物具有纯度高、毒性小、生物活性好等特点,已成为新药研发的热点。中晟全肽首创的多肽信息压缩技术(Peptide Information Compression Technology-PICT)可为多肽药物研发提供一个包含近5亿个多肽信息的宝贵“种子库”,首次实现了通过靶点盲筛发现多肽新药,解决了全球多肽新药研发中发现先导化合物的核心技术瓶颈,将显著缩短多肽药物研发周期,降低研发成本,带动多肽药物市场的繁荣。该技术已申请中国、美国、欧洲、加拿大、澳大利亚、日本等多国专利,并获得欧洲专利授权。

同时,中晟全肽采用多肽信息压缩技术,构建了具有独立自主知识产权的多肽全库,该技术大幅降低了肽库构建的成本和新药筛选的成本,建库效率提高6000倍。

据悉,中晟全肽的五肽全库已构建完成,已达成数千万元多肽库合同营收,获得销售回款超千万元,并与第三方合作完成了多肽库价值验证,多肽样品针对PD1/PDL1靶点已筛选出若干高活性化合物。此外,其自主建设的华南地区最大的高通量新药筛选与生物活性检测平台预计于2019年9月建成投入使用,并计划今年在美国成立子公司,启动国际市场拓展工作。

中晟全肽方面透露,公司将基于自主知识产权的多肽库,针对肿瘤、慢性炎症、糖尿病、心脑血管等多领域靶点开展新药筛选,加速研发管线布局,在未来5年将公司打造成为全球领先的多肽先导化合物及新药筛选技术服务提供商。

渤溢资本总经理朱艳飞表示:“中晟全肽目前是全球唯一利用多肽信息压缩技术构建具有独立自主知识产权的多肽全库与多肽药物发现的企业,在多肽库构建及新药筛选研发赛道拥有全球性领先优势。该技术平台的稀缺性突出,苗头化合物B147已取得阶段性的验证结果,已经具备开展新药商业化筛选服务的潜力。中晟全肽是拥有多种盈利模式的企业,未来合作想象空间巨大,符合渤溢基金围绕新药研发上下游产业链进行投资的策略,并且可以与渤溢基金已经投资的某“巨型新药种子库(小分子)”企业技术互补、业务协同”。

目前,全球多肽库用于新药发现仅有3家,另外两家为PeptiDream(日本)和 Bicycle Therapeutics。PeptiDream(日本)是一家从事肽类新药研发的生物技术公司,目前已有项目进入临床一期,年营业收入为4.08亿元人民币,最新市值在445亿元人民币;Bicycle Therapeutics的核心技术平台是基于“双环”形式的多肽库的药物筛选和优化,其上市文件披露了10个在研项目,包括5个聚焦癌症治疗的自主研发项目及5个合作开发项目。它们皆利用新型的多肽构建技术进行构建多肽分子,构建了巨型多肽库,大大提高了化合物库的多样性。

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    2019-07-28 lqvr
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    2019-07-28 zhao4618
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    2019-07-28 fusion
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    2019-07-27 CHANGE

    又是钱!医学需要投资呀,赞!

    0