Sci Rep:东南亚禽流感A(H7N9)病毒感染的流行病学和病毒学特征

2017-05-08 MedSci MedSci原创

近期,一项发表在杂志Sci Rep上的研究旨在调查东南亚两个家族群体中甲型流感(H7N9)确诊病例的流行病学、临床和病毒学特征。H7N9流行病学资料证实病例及其密切联系是通过对病历的访谈和回顾获得的。在这两个家庭群体的4名患者中,2例症状轻微,1例有严重症状,1例死亡。四名患者中3人有活禽或受污染环境的接触史。来自同一家族群聚者的H7N9病毒的完整基因组序列是高度同源的,来自两个家族群居者的4个分

近期,一项发表在杂志Sci Rep上的研究旨在调查东南亚两个家族群体中甲型流感(H7N9)确诊病例的流行病学、临床和病毒学特征。


H7N9流行病学资料证实病例及其密切联系是通过对病历的访谈和回顾获得的。在这两个家庭群体的4名患者中,2例症状轻微,1例有严重症状,1例死亡。四名患者中3人有活禽或受污染环境的接触史。

来自同一家族群聚者的H7N9病毒的完整基因组序列是高度同源的,来自两个家族群居者的4个分离的病毒在传播性、致病性、宿主适应和抗病毒药物抗性方面表现出H7N9病毒的病毒学特征。

此外,此项研究结果还发现,A / Fujian / 18/2015病毒株含有另外的血凝素G225D替代物,其优先结合α2,6-连接的唾液酸。

此项项研究的结果表明,一个家庭群体通过常见的家禽暴露或受污染的环境感染,另一个家庭群体更可能通过人-人的途径感染

原始出处:
Xie J, Weng Y, et al. Epidemiological, clinical, and virologic features of two family clusters of avian influenza A (H7N9) virus infections in Southeast China. Sci Rep. 2017 May 4;7(1):1512. doi: 10.1038/s41598-017-01761-w.

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    2017-05-14 lou.minghong

    有相关指南吗?

    0

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    2017-05-10 xugumin
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    2017-05-10 周虎
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    2017-05-09 131****2916

    还不错嘛,学习到了

    0

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    2017-05-09 龙胆草

    学习了,谢谢分享

    0

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    2017-05-09 微笑人参

    冷源元(天然气,石油)被开采有关,制热源汽车太多

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=197975, encodeId=6e1019e97526, content=有相关指南吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib2JlGvwpAibiaovVhfA9DbO7X7JLGGjM4Cic6oMgxLdnuS9piaP9cnG2OwIbkzHvX0qzS1boibyYNqR5vHZu7HQs5EIB/0, createdBy=298d1398341, createdName=lou.minghong, createdTime=Sun May 14 12:32:51 CST 2017, time=2017-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1411262, encodeId=a2fa1411262d0, content=<a href='/topic/show?id=91e96538eee' target=_blank style='color:#2F92EE;'>#流行病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65387, encryptionId=91e96538eee, topicName=流行病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Wed May 10 08:54:00 CST 2017, time=2017-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1477537, encodeId=744114e7537fa, content=<a href='/topic/show?id=9f7d8411fc' target=_blank style='color:#2F92EE;'>#H7N9#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8411, encryptionId=9f7d8411fc, topicName=H7N9)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e1f27379114, createdName=ms117281293605716, createdTime=Wed May 10 08:54:00 CST 2017, time=2017-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1603331, encodeId=ca77160333115, content=<a href='/topic/show?id=4800e091642' target=_blank style='color:#2F92EE;'>#病毒学#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70916, encryptionId=4800e091642, topicName=病毒学)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2ed319029923, createdName=周虎, createdTime=Wed May 10 08:54:00 CST 2017, time=2017-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=195809, encodeId=dfeb19580980, content=还不错嘛,学习到了, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04f22055142, createdName=131****2916, createdTime=Tue May 09 12:01:27 CST 2017, time=2017-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=195653, encodeId=4e5919565329, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Tue May 09 06:45:31 CST 2017, time=2017-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=195604, encodeId=ae2e195604ea, content=冷源元(天然气,石油)被开采有关,制热源汽车太多, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220317/1c3b2db4747d42e88e5018b394979434/be0fcebf07344e9ab886c37c502e2f29.jpg, createdBy=6bb22051299, createdName=微笑人参, createdTime=Tue May 09 06:10:53 CST 2017, time=2017-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=195488, encodeId=a504195488a9, content=认真解读!, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/PiajxSqBRaEJxc6nn7icgbgOgdfY0Pfp9ibU1Qx7NW3xia5ic9D8XEuhhguJept0RdDlDK8ps5Qo2qkz0XmGcAIibibOA/0, createdBy=56f11370106, createdName=点滴累积改变自己, createdTime=Mon May 08 20:14:24 CST 2017, time=2017-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=195475, encodeId=73741954e511, content=这个必须了解深刻点, beContent=null, objectType=article, channel=null, level=null, likeNumber=15, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04f22055142, createdName=131****2916, createdTime=Mon May 08 18:15:27 CST 2017, time=2017-05-08, status=1, ipAttribution=)]
    2017-05-08 点滴累积改变自己

    认真解读!

    0

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    2017-05-08 131****2916

    这个必须了解深刻点

    0

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