Gastroenterology:高蛋白饮食有助改善糖尿病患者的脂肪肝

2016-11-04 佚名 生物谷

根据德国人类营养研究所对2型糖尿病患者进行的一项最新营养学研究,他们发现高蛋白饮食能够降低肝脏脂肪含量,6周内最多可将肝脏脂肪含量减少48%。饮食究竟以植物蛋白还是动物蛋白为主并不重要。相关研究结果发表在国际学术期刊Gastroenterology上。世界范围内多项研究已经调查过高蛋白饮食对人类代谢的影响。在许多研究中,科学家们观察到高蛋白饮食对体重,肝脏脂肪含量,血脂水平,长期血糖水平以及肌肉含


根据德国人类营养研究所对2型糖尿病患者进行的一项最新营养学研究,他们发现高蛋白饮食能够降低肝脏脂肪含量,6周内最多可将肝脏脂肪含量减少48%。饮食究竟以植物蛋白还是动物蛋白为主并不重要。相关研究结果发表在国际学术期刊Gastroenterology上。

世界范围内多项研究已经调查过高蛋白饮食对人类代谢的影响。在许多研究中,科学家们观察到高蛋白饮食对体重,肝脏脂肪含量,血脂水平,长期血糖水平以及肌肉含量都有有益作用。但是一些研究也发现高蛋白摄入可以降低胰岛素活性,影响肾脏功能。由于不同研究既观察到高蛋白饮食的积极作用也观察到负面作用,因此德国人类营养研究所的研究人员提出问题,蛋白质来源是否是导致产生不同作用的决定因素。因此在这项研究中,他们研究了两种高蛋白饮食对37名参与者的代谢产生的影响,这些参与者年龄在49岁到78岁之间,都患有2型糖尿病,大部分人还存在脂肪肝。这两种高蛋白饮食的唯一差别是蛋白质来源(植物来源和动物来源)。

为了保证研究期间参与者们的体重能够保持稳定,研究人员为每个人调整了饮食的总热量,并随机安排参与者们选择其中一种高蛋白饮食。结果表明所有研究参与者都从高蛋白饮食中得到获益,与蛋白来源无关,并且没有观察到高蛋白饮食对肾脏功能和葡萄糖代谢的不良影响。肝脏脂肪含量下降最为显著,一半参与者下降了超过50%,与此同时研究人员还观察到参与者们的肝脏脂质代谢出现有利变化,胰岛素敏感性得到改善,血液中FGF21的水平出现了显著下降。之前有研究发现肝脏合成的FGF21能够影响包括脂肪组织在内的多个器官组织,特别是对于超重和肥胖的人来说,他们血液中的FGF21水平通常较高。

研究人员表示,还需要更大型更长期的研究来更加深入的理解其中的代谢机制以及高蛋白饮食对代谢的长期影响,同时观察年轻病人是否也能从这种饮食方式中获益。

总的来说,研究人员认为将研究结果和各种环境相关因素考虑在内,他们更倾向于推荐人们把植物性食物当作蛋白质的主要来源。

原始出处

Mariya Markova1, 2,Olga Pivovarova1, 2, 3, ∗, Silke Hornemann1, 2, Stephanie Sucher1, 2, Turid Frahnow1, 2, Katrin Wegner4, Jürgen Machann2, 5, 6, Klaus Jürgen Petzke1, Johannes Hierholzer7, Ralf Lichtinghagen8, Christian Herder2, 9, Maren Carstensen-Kirberg2, 9, Michael Roden2, 9, 10, Natalia Rudovich1, 2, 3, Susanne Klaus1, Ralph Thomann11, Rosemarie Schneeweiss12, Sascha Rohn4, 12, Andreas F.H. Pfeiffer1.Isocaloric Diets High in Animal or Plant Protein Reduce Liver fat and Inflammation in Individuals with Type 2 Diabetes.Gastroenterology.2016


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    2016-11-06 海豹
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    2016-11-06 医张生

    学习了。持续关注。吃肉

    0

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