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Am Heart J：心率恢复程度可评估CAD患者预后

2018-07-05 国际循环编辑部 国际循环

心率恢复HRRCAD预后
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目前，针对冠状动脉疾病（CAD）患者，常规门诊治疗缺乏一套简单易行的身体和死亡危险测量方法。心率恢复（HRR）是非侵入性的手段，易于在门诊患者中施行。此前有研究表明，在最初的几分钟内，延迟性动作后HRR与某些类型人群的死亡率相关。但目前缺少关于延迟性HRR对死亡率的预测价值的全面综述。近期，发表于American Heart Journal的一项荟萃分析对CAD患者延迟HRR的预后价值进行评估。

目前，针对冠状动脉疾病（CAD）患者，常规门诊治疗缺乏一套简单易行的身体和死亡危险测量方法。心率恢复（HRR）是非侵入性的手段，易于在门诊患者中施行。此前有研究表明，在最初的几分钟内，延迟性动作后HRR与某些类型人群的死亡率相关。但目前缺少关于延迟性HRR对死亡率的预测价值的全面综述。近期，发表于American Heart Journal的一项荟萃分析对CAD患者延迟HRR的预后价值进行评估。

研究人员在相关数据库中进行系统检索，筛选关于HRR和CAD患者心血管事件发生危险或死亡率的相关研究，通过比较延迟HRR和非延迟HRR的HR值进行随机效应荟萃分析。研究人员共纳入4项研究，按照质量评级分为中级和高级各2项，共涉及2428例CAD患者。延迟HRR的定义为恢复期心率≤12至≤21次/分钟。在2.0~9.8年的随访期内，共有151例（6.2%）患者死亡。研究只收集到死亡率的数据，且异质性很小（I2=32%：P=0.23）。从其中3个研究中采集到的未调整死亡率HR=5.8（95%CI：3.2~10.4）。

这项研究结果证实，延迟HRR确实与全因死亡率存在显著相关性。因此，HRR可以作为监控CAD患者的日常运动测试的手段。当然，是否应将HHR加入当前的危险评分体系仍有待进一步研究证实。

原始出处：
Sangeeta Lachman,Michel S. Terbraak, et al. The prognostic value of heart rate recovery in patients with coronary artery disease: A systematic review and meta-analysis. American Heart Journal. May 2018 Volume 199, Pages 163–169.

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    2019-05-26 bnurmamat

    #患者预后#

    0

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    2018-07-14 jyzxjiangqin

    心率恢复程度可评估.

    0

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    2018-07-07 zhaojie88

    #ART#

    0

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    2018-07-07 slcumt

    #HEART#

    0

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    2018-07-07 jyzxjiangqin

    心率恢复程度可评估CAD患者预后.

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1691988, encodeId=659716919881c, content=<a href='/topic/show?id=a450530853c' target=_blank style='color:#2F92EE;'>#患者预后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53085, encryptionId=a450530853c, topicName=患者预后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8f4729287700, createdName=bnurmamat, createdTime=Sun May 26 23:51:00 CST 2019, time=2019-05-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=331544, encodeId=3405331544d6, content=心率恢复程度可评估., beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sat Jul 14 14:28:14 CST 2018, time=2018-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356842, encodeId=dd5513568423f, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sat Jul 07 12:51:00 CST 2018, time=2018-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562932, encodeId=fb311562932b1, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Sat Jul 07 12:51:00 CST 2018, time=2018-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=329969, encodeId=323b3299691d, content=心率恢复程度可评估CAD患者预后., beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sat Jul 07 11:55:43 CST 2018, time=2018-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=329588, encodeId=769a3295881c, content=学习了.涨知识了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, createdBy=29392048316, createdName=王秀, createdTime=Thu Jul 05 22:03:18 CST 2018, time=2018-07-05, status=1, ipAttribution=)]
    2018-07-05 王秀

    学习了.涨知识了!

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