JAMA Pediatr:中国30个省,324个地级市,1300342名孕产妇参与研究证实PM1超标可导致早产

2018-01-03 zhangfan MedSci原创

研究认为,大气中PM1污染与中国各地的新生儿早产显著相关

大气颗粒物污染与早产相关,近日研究人员进一步考察了PM1与早产的相关性。

研究在中国开展,30个省的324个地级市,总计1300342名健康单胎产妇参与研究。研究通过卫星遥感估计孕妇家庭地址附件每周的PM1浓度。采用Cox比例风险回归分析妊娠特异性PM1与早产之间的关系,调整温度、季节性、空间变化和个体协变量因素。

研究包含了1300342名孕20-45周女性,其中104585人(8.0%)发生早产。调整后发现,整个孕期PM1浓度超过10 μg/m3与早产显著相关(HR,1.09;95% CI,1.09-1.10),与孕28-31周早产显著相关(HR, 1.20; 95% CI, 1.18-1.23),与孕20-27周的极端早产显著相关(HR,1.29;95% CI,1.25-1.34)。30-50岁的高龄产妇(HR,1.13;95% CI,1.11-1.14)、孕前超重 (HR,1.13;95% CI,1.11-1.15)、农村地区(HR,1.09;95% CI,1.09-1.10)、农民(HR,1.10;95% CI,1.09-1.11)以及秋天怀孕 (HR,1.48;95% CI,1.46-1.50)的孕产妇对PM1的敏感性更高。

研究认为,大气中PM1污染与中国各地的新生儿早产显著相关。

原始出处:


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    2018-09-09 feather89
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    2018-08-16 医者仁心
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    2018-01-03 董海鹏

    人与自然如何才能平衡

    0

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    2018-01-03 1e0f8808m18(暂无匿称)

    环境因素严重影响人类健康.

    0

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    2018-01-03 圣艮山

    学习了不少事情

    0

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