J Clin Med:高强度间歇训练与心力衰竭患者长期生存率提高相关

2020-03-19 MedSci原创 MedSci原创

这项配对对照队列研究探讨了2009至2016年间高强度间歇训练(HIIT)对心衰(HF)患者的左心室(LV)尺寸和存活率的影响。

这项配对对照队列研究探讨了2009至2016年间高强度间歇训练(HIIT)对心衰(HF)患者的左心室(LV)尺寸和存活率的影响。

 

纳入进行了多学科疾病管理计划(MDP)的HF患者。年龄(平均(95%置信区间))为62.8(60.1-65.5)岁的非运动参与者被分为MDP组(n = 101)。参加了36次HIIT训练的年龄为61.5(58.7-64.2)岁的参与者被分为HIIT组(n = 101)。在8年的随访期内评估了峰值耗氧量(VO2peak)和左室形状。纵向观察确定5年全因死亡率危险因素和总生存率。

 

结果显示,运动训练后,HIIT组的VO2峰值增加了14-20%。VO2peak每增加1mL / kg / min可使患者5年死亡率提高58%。左室收缩末期直径增加(LVESD)与死亡率增加显著相关(p = 0.0198)。与非运动参与者相比,HIIT参与者的8个月生存率显著提高(p = 0.044)。 VO2peak≥14.0mL / kg / min且LVESD <44 mm的HF患者的5年生存率(98.2%)明显高于VO2peak较低且LVESD较高的患者(57.3%)。

 

总之,该研究结果表明,HIIT诱导的VO2peak升高和LVESD降低均与HF患者的生存期改善有关。

 

原始出处:

 

Chih-Chin HsuTieh-Cheng Fu, et al., High-Intensity Interval Training is Associated with Improved Long-Term Survival in Heart Failure Patients. J Clin Med. 2019 Mar; 8(3): 409. doi: 10.3390/jcm8030409

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    2020-03-21 aids219
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