Int J Cardiol:法洛四联症患者右心房功能异常!

2017-07-10 xing.T MedSci原创

由此可见,TOF患者RALS、RAEDVi和RAEF异常。降低的RALS表明RA储器功能下降。由于它们与其他功能性RV指数相关,这些异常可能代表TOF患者慢性RV功能障碍的RA舒张负担。

近日,心血管领域权威杂志International Journal of Cardiology上发表了一篇研究文章,研究人员假设法洛四联症(TOF)患者右心房(RA)的功能异常。研究人员前瞻性地招募了TOF患者,这些TOF患者进行了心血管磁共振(CMR)、超声心动图和运动应力检查。研究人员使用CMR特征跟踪(FT)测定右心房纵向应变(RALS)和右心室纵向应变(RALS)峰值,并且分析了其与RA和RV舒张末期容积(EDVi)和射血分数(EF)之间的相关性。该研究队列有311名受试者:171名TOF患者(94名男性,18.2±8岁)和140名健康对照者(69名男性,16.4±11岁)。TOF患者RAEDVi、RALS、RVEDVi、RVLS、RAEF和RVEF分别为60.8±17.1ml/m2、13.6±5.7%、120.3±30.3ml/m2、12.3±4.2%、32.5±9.9%和51.2±8.4%,并且各个指标与对照者存在差异:51.7±15.7ml/m2、27±10.1%、74±19ml/m2、18.5±5.3%、54±8%和62.5±5.5%(P<0.001)。RAEDVi和R

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    2018-05-01 wgsun
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    2017-07-12 sodoo
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    2017-07-10 半夏微凉

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