Front Physiol:维生素C摄入和前列腺癌风险研究

2018-09-29 AlexYang MedSci原创

维生素C是一种还原物质和自由基清除物质,在细胞内的质膜上具有抗氧化作用。基于这些特性,相关研究人员调查了维生素C在癌症发生率上的影响。但是基于大群体的与前列腺癌相关的研究很少,并且证据显示倾向于认为维生素C与前列腺癌没有相关性。尽管如此,许多之前的研究忽视了前列腺癌的恶化,以及筛选和组织检测,这也导致了倾向性相关性的存在。最近,有研究人员在加拿大蒙特利尔进行了基于大群体的研究。研究发现,日常摄入维

维生素C是一种还原物质和自由基清除物质,在细胞内的质膜上具有抗氧化作用。基于这些特性,相关研究人员调查了维生素C在癌症发生率上的影响。但是基于大群体的与前列腺癌相关的研究很少,并且证据显示倾向于认为维生素C与前列腺癌没有相关性。尽管如此,许多之前的研究忽视了前列腺癌的恶化,以及筛选和组织检测,这也导致了倾向性相关性的存在。

最近,有研究人员在加拿大蒙特利尔进行了基于大群体的研究。研究发现,日常摄入维生素C(OR for upper vs. lower tertile: 0.95, 95%CI 0.77, 1.18)、日常维生素C的补充或者多重维生素的补充(OR 0.90, 95%CI 0.76-1.05)与总的前列腺癌之间没有相关性。研究人员的分析考虑了疾病的恶化和参与者最近经历PSA筛选的限制,因此限制了非案例中未诊断癌症的可能性,且产生了与主要分析一致的研究结果。

最后,研究人员指出,他们的发现表明了维生素C日常食用或者补充与前列腺癌总的发生率或者前列腺癌诊断时的等级没有相关性。基于研究结果和其他的研究结果,维生素C的摄入在前列腺癌的预防方面可能没有前景。

原始出处:

Parent ME, Richard H, Rousseau MC. Vitamin C Intake and Risk of Prostate Cancer: The Montreal PROtEuS Study. Front Physiol. 4 Sep 2018.

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    2019-01-05 sjq027
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    2018-10-12 一个字-牛

    学习了谢谢分享

    0

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    2018-09-29 liumin1987

    嗯嗯,学习学习。

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