Circulation:无症状预激综合征常规有创干预受质疑

2012-05-06 高晓方译 医学论坛网

  加拿大学者的一项荟萃分析表明,大部分无症状性预激综合征患者的心脏猝死发病率较低,室上性心动过速(SVT)风险亦较低,因此可能无需常规有创治疗。论文于2012年4月24日在线发表于《循环》(Circulation)杂志。   在伴有无症状性预激的患者中,心脏猝死的发病率和其风险管理尚有待明确。研究者对EMBASE和Medline数据库中的前瞻性、回顾性、随机或队列研究进行了系统检索,并纳入了涉

  加拿大学者的一项荟萃分析表明,大部分无症状性预激综合征患者的心脏猝死发病率较低,室上性心动过速(SVT)风险亦较低,因此可能无需常规有创治疗。论文于2012年4月24日在线发表于《循环》(Circulation)杂志。

  在伴有无症状性预激的患者中,心脏猝死的发病率和其风险管理尚有待明确。研究者对EMBASE和Medline数据库中的前瞻性、回顾性、随机或队列研究进行了系统检索,并纳入了涉及未接受消融的无症状性预激综合征患者的研究。

  共有20项研究符合纳入标准,其中包括1869例患者。受试者主要为男性,平均年龄介于7至43岁之间。在11722人年随访期间共报告10例心脏猝死。心脏猝死风险估计值为1.25/1000人年。在来自于18项研究的9884人年随访期间共报告156例室上性心动过速(SVT)。SVT的风险为16起事件/1000人年随访。与成人相比,儿童的心脏猝死和SVT事件率相对较高,但无统计学差异。

  链接:

  Risk of Arrhythmia and Sudden Death in Patients with Asymptomatic Pre-Excitation: A Meta Analysis

  



    

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    2012-06-20 saikp
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    2012-05-07 zhouqu_8
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