Ann Intern Med:胃食管反流病内镜筛查建议

2012-12-07 小哲 编译 Ann Intern Med

  上消化道内镜筛查常在诊断和管理胃食管反流病(gastroesophageal reflux disease,GERD)患者时使用。12月4日,美国《内科学年鉴(Annals of Internal Medicine)》刊载的一项指南指出,内科医生对低风险GERD患者过度进行上消化道内镜检查,没有促进患者转归反而导致更高的医疗花费。[Ann In

  上消化道内镜筛查常在诊断和管理胃食管反流病(gastroesophageal reflux disease,GERD)患者时使用。12月4日,美国《内科学年鉴(Annals of Internal Medicine)》刊载的一项指南指出,内科医生对低风险GERD患者过度进行上消化道内镜检查,没有促进患者转归反而导致更高的医疗花费。[Ann Intern Med. 2012;157:808-816.]

  内镜检查是消化道疾病诊断和管理的重大突破。然而,不恰当的检查不但没有益处反而可能增加医疗成本。回顾往期研究数据表明,上消化道内镜检查只在少数情况下用于胃食管反流病的诊断。

  第一,指南作者推荐所有胃灼热和GERD的男性、女性患者出现吞咽困难、出血、贫血、体重减轻和再发性呕吐时进行上消化道内镜检查。作者说,在这些情况下上消化道内镜检查是有价值的,因为可以识别临床必要的信息,比如胃癌或食管癌、前肠出血病灶,以及食管或幽门狭窄。

  第二,作者推荐下列患者应进行上消化道内镜检查:持续4~8周质子泵抑制剂(proton pump inhibitor,PPI)治疗的GERD男性、女性患者;经过2个月PPI治疗后评估康复并且排除巴雷特食管(Barrett's esophagus)的重度腐蚀性食管炎的男性、女性患者;有食管狭窄病史并且有周期性吞咽困难症状的男性、女性患者。

  第三,指南推荐下述人群进行上消化道内镜检查:50岁以上并有夜间反流症、吸烟和体质指数偏高等风险因子的慢性GERD男性患者需检查是否有食管癌和巴雷特食管;对于有巴雷特食管病史的男性、女性患者进行监测评估,已经确诊为巴雷特食管的患者建议每3~5年进行上消化道内镜复检,出现轻度至重度的异型增生时,由于癌变风险增加,建议定期进行内镜筛查。


Upper Endoscopy for Gastroesophageal Reflux Disease: Best Practice Advice From the Clinical Guidelines Committee of the American College of Physicians 



    

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    2012-12-09 zhouqu_8
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    2012-12-09 feifers
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