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Gastroenterology：新辅助化放疗序贯肝移植对肝门部胆管癌有效

2012-07-09 MedSci MedSci原创

肝门部胆管癌新辅助治疗肝移植
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    《胃肠病学》杂志(Gastroenterology)7月刊发的一项多中心回顾性研究显示，新辅助化放疗序贯肝移植治疗不可切除性肝门部胆管癌有效且合理(Gastroenterology 2012 July [doi: 10.1053/j.gastro.2012.04.008])。      2006年，基于化放疗/移植方案的

    《胃肠病学》杂志(Gastroenterology)7月刊发的一项多中心回顾性研究显示，新辅助化放疗序贯肝移植治疗不可切除性肝门部胆管癌有效且合理(Gastroenterology 2012 July [doi: 10.1053/j.gastro.2012.04.008])。      2006年，基于化放疗/移植方案的优异单中心预后报告，联合器官共享网络(UNOS)建立了标准化的肝门部胆管癌终末期肝病模型(MELD)例外标准(Liver Transpl. 2006;12:S95-7)。     在这项研究中，梅奥医院的Sarwa Darwish Murad博士及其同事分析了1993~2010年美国12家采用新辅助疗法和肝移植治疗≥3例肝门部胆管癌患者的大手术量移植中心的数据。     共有287例患者达到研究标准。分别有99%、75%、98%和65%的患者完成外照射、近距离放射治疗、放射增敏治疗和维持化疗。71例(24.7%)患者在中位4

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    2015-10-11 hlycom3356

    感谢作者分享

    0

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    2012-11-21 charl1234576

    #新辅助#

    0

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    2012-12-21 jktdtl

    #Gastroenterol#

    0

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    2013-06-14 许安

    #GAS#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=38370, encodeId=ff9e383e0d6, content=感谢作者分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=178, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=332823945, createdName=hlycom3356, createdTime=Sun Oct 11 20:47:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1678466, encodeId=34f016e846683, content=<a href='/topic/show?id=110c5869153' target=_blank style='color:#2F92EE;'>#新辅助#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58691, encryptionId=110c5869153, topicName=新辅助)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=941f27706894, createdName=charl1234576, createdTime=Wed Nov 21 19:57:00 CST 2012, time=2012-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063817, encodeId=ba35206381ef1, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Fri Dec 21 15:57:00 CST 2012, time=2012-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2071456, encodeId=e80e20e1456ff, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Fri Jun 14 00:57:00 CST 2013, time=2013-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1710606, encodeId=3f5f1e10606af, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Fri Nov 23 08:57:00 CST 2012, time=2012-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1504139, encodeId=d9db15041391b, content=<a href='/topic/show?id=7730e85412' target=_blank style='color:#2F92EE;'>#Gastroenterology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Wed Jul 11 06:57:00 CST 2012, time=2012-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1510537, encodeId=0ece151053e96, content=<a href='/topic/show?id=589b815113c' target=_blank style='color:#2F92EE;'>#肝门部胆管癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81511, encryptionId=589b815113c, topicName=肝门部胆管癌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5cae10200112, createdName=小刀医生, createdTime=Wed Jul 11 06:57:00 CST 2012, time=2012-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1628232, encodeId=7cce16282329f, content=<a href='/topic/show?id=9a4e83503e4' target=_blank style='color:#2F92EE;'>#胆管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83503, encryptionId=9a4e83503e4, topicName=胆管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c21721182790, createdName=cmj15wellington, createdTime=Wed Jul 11 06:57:00 CST 2012, time=2012-07-11, status=1, ipAttribution=)]
    2012-11-23 ms24272190615788285182

    #AST#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=38370, encodeId=ff9e383e0d6, content=感谢作者分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=178, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=332823945, createdName=hlycom3356, createdTime=Sun Oct 11 20:47:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1678466, encodeId=34f016e846683, content=<a href='/topic/show?id=110c5869153' target=_blank style='color:#2F92EE;'>#新辅助#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58691, encryptionId=110c5869153, topicName=新辅助)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=941f27706894, createdName=charl1234576, createdTime=Wed Nov 21 19:57:00 CST 2012, time=2012-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063817, encodeId=ba35206381ef1, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Fri Dec 21 15:57:00 CST 2012, time=2012-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2071456, encodeId=e80e20e1456ff, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Fri Jun 14 00:57:00 CST 2013, time=2013-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1710606, encodeId=3f5f1e10606af, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Fri Nov 23 08:57:00 CST 2012, time=2012-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1504139, encodeId=d9db15041391b, content=<a href='/topic/show?id=7730e85412' target=_blank style='color:#2F92EE;'>#Gastroenterology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Wed Jul 11 06:57:00 CST 2012, time=2012-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1510537, encodeId=0ece151053e96, content=<a href='/topic/show?id=589b815113c' target=_blank style='color:#2F92EE;'>#肝门部胆管癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81511, encryptionId=589b815113c, topicName=肝门部胆管癌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5cae10200112, createdName=小刀医生, createdTime=Wed Jul 11 06:57:00 CST 2012, time=2012-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1628232, encodeId=7cce16282329f, content=<a href='/topic/show?id=9a4e83503e4' target=_blank style='color:#2F92EE;'>#胆管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83503, encryptionId=9a4e83503e4, topicName=胆管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c21721182790, createdName=cmj15wellington, createdTime=Wed Jul 11 06:57:00 CST 2012, time=2012-07-11, status=1, ipAttribution=)]
    2012-07-11 heli0118

    #Gastroenterology#

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=38370, encodeId=ff9e383e0d6, content=感谢作者分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=178, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=332823945, createdName=hlycom3356, createdTime=Sun Oct 11 20:47:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1678466, encodeId=34f016e846683, content=<a href='/topic/show?id=110c5869153' target=_blank style='color:#2F92EE;'>#新辅助#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58691, encryptionId=110c5869153, topicName=新辅助)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=941f27706894, createdName=charl1234576, createdTime=Wed Nov 21 19:57:00 CST 2012, time=2012-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063817, encodeId=ba35206381ef1, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Fri Dec 21 15:57:00 CST 2012, time=2012-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2071456, encodeId=e80e20e1456ff, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Fri Jun 14 00:57:00 CST 2013, time=2013-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1710606, encodeId=3f5f1e10606af, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Fri Nov 23 08:57:00 CST 2012, time=2012-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1504139, encodeId=d9db15041391b, content=<a href='/topic/show?id=7730e85412' target=_blank style='color:#2F92EE;'>#Gastroenterology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Wed Jul 11 06:57:00 CST 2012, time=2012-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1510537, encodeId=0ece151053e96, content=<a href='/topic/show?id=589b815113c' target=_blank style='color:#2F92EE;'>#肝门部胆管癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81511, encryptionId=589b815113c, topicName=肝门部胆管癌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5cae10200112, createdName=小刀医生, createdTime=Wed Jul 11 06:57:00 CST 2012, time=2012-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1628232, encodeId=7cce16282329f, content=<a href='/topic/show?id=9a4e83503e4' target=_blank style='color:#2F92EE;'>#胆管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83503, encryptionId=9a4e83503e4, topicName=胆管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c21721182790, createdName=cmj15wellington, createdTime=Wed Jul 11 06:57:00 CST 2012, time=2012-07-11, status=1, ipAttribution=)]
    2012-07-11 小刀医生

    #肝门部胆管癌#

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=38370, encodeId=ff9e383e0d6, content=感谢作者分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=178, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=332823945, createdName=hlycom3356, createdTime=Sun Oct 11 20:47:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1678466, encodeId=34f016e846683, content=<a href='/topic/show?id=110c5869153' target=_blank style='color:#2F92EE;'>#新辅助#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58691, encryptionId=110c5869153, topicName=新辅助)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=941f27706894, createdName=charl1234576, createdTime=Wed Nov 21 19:57:00 CST 2012, time=2012-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063817, encodeId=ba35206381ef1, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Fri Dec 21 15:57:00 CST 2012, time=2012-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2071456, encodeId=e80e20e1456ff, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Fri Jun 14 00:57:00 CST 2013, time=2013-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1710606, encodeId=3f5f1e10606af, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Fri Nov 23 08:57:00 CST 2012, time=2012-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1504139, encodeId=d9db15041391b, content=<a href='/topic/show?id=7730e85412' target=_blank style='color:#2F92EE;'>#Gastroenterology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Wed Jul 11 06:57:00 CST 2012, time=2012-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1510537, encodeId=0ece151053e96, content=<a href='/topic/show?id=589b815113c' target=_blank style='color:#2F92EE;'>#肝门部胆管癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81511, encryptionId=589b815113c, topicName=肝门部胆管癌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5cae10200112, createdName=小刀医生, createdTime=Wed Jul 11 06:57:00 CST 2012, time=2012-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1628232, encodeId=7cce16282329f, content=<a href='/topic/show?id=9a4e83503e4' target=_blank style='color:#2F92EE;'>#胆管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83503, encryptionId=9a4e83503e4, topicName=胆管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c21721182790, createdName=cmj15wellington, createdTime=Wed Jul 11 06:57:00 CST 2012, time=2012-07-11, status=1, ipAttribution=)]
    2012-07-11 cmj15wellington

    #胆管#

    0