Sci Rep:多吃鱼可降低结直肠的发病风险

2015-09-05 MedSci MedSci原创

Nature:多吃鱼可降低结直肠的发病风险近日,来自中山大学的一项研究表明,吃鱼可降低结直肠癌的发病率,该研究结果于8月25日在线发表于《Nature》。关于某些鱼的摄入与结直肠癌发病风险之间的关系仍存在争议。该项大型的队列研究旨在探讨中国人群某些鱼的摄入与结直肠癌发病风险之间的关系。研究纳入了2010年7月至2014年11月期间的1189 例结直肠癌患者以及1189名年龄性别与之匹配的对照者。以

近日,来自中山大学的一项研究表明,吃鱼可降低结直肠癌的发病率,该研究结果于8月25日在线发表于Sci Rep上。



关于某些鱼的摄入与结直肠癌发病风险之间的关系仍存在争议。该项大型的队列研究旨在探讨中国人群某些鱼的摄入与结直肠癌发病风险之间的关系。

研究纳入了2010年7月至2014年11月期间的1189 例结直肠癌患者以及1189名年龄性别与之匹配的对照者。以访谈形式对所有受试者进行问卷调查以评估其饮食的摄入。

校正各混杂因素后,采用多因素 Logistic 回归分析模型评估比值比(OR)及95%可信区间(95%CI)。结果发现,淡水鱼的摄入可显著降低结直肠癌的发病风险。校正混杂因素后,与最低四分位数相比,最高四分位数显示结直肠癌的发病风险降低了53%(OR 0.47,95% CI= 0.36–0.60, P< 0.01)。此外,研究人员还发现,海鱼(OR 0.79, 95%CI= 0.62–0.99, P< 0.01)及鲜鱼(OR 0.49,95%CI= 0.38–0.62, P< 0.01)的摄入也可降低结直肠癌的发病风险。然而,并未发现干/咸鱼以及贝类的摄入与结直肠癌的发病风险之间存在统计学意义。

总而言之,该研究结果表明,摄入较多的淡水鱼、海鱼及鲜鱼类可降低结直肠癌的发病风险。

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  1. [GetPortalCommentsPageByObjectIdResponse(id=178565, encodeId=246d1e856590, content=日本结直肠发生率多少?, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160922/IMG57E3868CA52422858.jpg, createdBy=da5d1716996, createdName=小马飞刀, createdTime=Sat Mar 04 10:48:15 CST 2017, time=2017-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1452766, encodeId=49581452e6677, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Sun Sep 06 15:31:00 CST 2015, time=2015-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=36432, encodeId=8e95364321f, content=属猫,就喜欢吃鱼, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=481c1648220, createdName=柳青, createdTime=Sun Sep 06 09:58:00 CST 2015, time=2015-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=36425, encodeId=372b364255f, content=不喜欢吃鱼咋办, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Sat Sep 05 11:40:00 CST 2015, time=2015-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=36424, encodeId=1e0f36424c8, content=有意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Sat Sep 05 09:24:00 CST 2015, time=2015-09-05, status=1, ipAttribution=)]
    2017-03-04 小马飞刀

    日本结直肠发生率多少?

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=178565, encodeId=246d1e856590, content=日本结直肠发生率多少?, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160922/IMG57E3868CA52422858.jpg, createdBy=da5d1716996, createdName=小马飞刀, createdTime=Sat Mar 04 10:48:15 CST 2017, time=2017-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1452766, encodeId=49581452e6677, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Sun Sep 06 15:31:00 CST 2015, time=2015-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=36432, encodeId=8e95364321f, content=属猫,就喜欢吃鱼, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=481c1648220, createdName=柳青, createdTime=Sun Sep 06 09:58:00 CST 2015, time=2015-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=36425, encodeId=372b364255f, content=不喜欢吃鱼咋办, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Sat Sep 05 11:40:00 CST 2015, time=2015-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=36424, encodeId=1e0f36424c8, content=有意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Sat Sep 05 09:24:00 CST 2015, time=2015-09-05, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=178565, encodeId=246d1e856590, content=日本结直肠发生率多少?, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160922/IMG57E3868CA52422858.jpg, createdBy=da5d1716996, createdName=小马飞刀, createdTime=Sat Mar 04 10:48:15 CST 2017, time=2017-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1452766, encodeId=49581452e6677, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Sun Sep 06 15:31:00 CST 2015, time=2015-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=36432, encodeId=8e95364321f, content=属猫,就喜欢吃鱼, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=481c1648220, createdName=柳青, createdTime=Sun Sep 06 09:58:00 CST 2015, time=2015-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=36425, encodeId=372b364255f, content=不喜欢吃鱼咋办, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Sat Sep 05 11:40:00 CST 2015, time=2015-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=36424, encodeId=1e0f36424c8, content=有意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Sat Sep 05 09:24:00 CST 2015, time=2015-09-05, status=1, ipAttribution=)]
    2015-09-06 柳青

    属猫,就喜欢吃鱼

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=178565, encodeId=246d1e856590, content=日本结直肠发生率多少?, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160922/IMG57E3868CA52422858.jpg, createdBy=da5d1716996, createdName=小马飞刀, createdTime=Sat Mar 04 10:48:15 CST 2017, time=2017-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1452766, encodeId=49581452e6677, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Sun Sep 06 15:31:00 CST 2015, time=2015-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=36432, encodeId=8e95364321f, content=属猫,就喜欢吃鱼, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=481c1648220, createdName=柳青, createdTime=Sun Sep 06 09:58:00 CST 2015, time=2015-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=36425, encodeId=372b364255f, content=不喜欢吃鱼咋办, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Sat Sep 05 11:40:00 CST 2015, time=2015-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=36424, encodeId=1e0f36424c8, content=有意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Sat Sep 05 09:24:00 CST 2015, time=2015-09-05, status=1, ipAttribution=)]
    2015-09-05 xiaotaiyang1

    不喜欢吃鱼咋办

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=178565, encodeId=246d1e856590, content=日本结直肠发生率多少?, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160922/IMG57E3868CA52422858.jpg, createdBy=da5d1716996, createdName=小马飞刀, createdTime=Sat Mar 04 10:48:15 CST 2017, time=2017-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1452766, encodeId=49581452e6677, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Sun Sep 06 15:31:00 CST 2015, time=2015-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=36432, encodeId=8e95364321f, content=属猫,就喜欢吃鱼, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=481c1648220, createdName=柳青, createdTime=Sun Sep 06 09:58:00 CST 2015, time=2015-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=36425, encodeId=372b364255f, content=不喜欢吃鱼咋办, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Sat Sep 05 11:40:00 CST 2015, time=2015-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=36424, encodeId=1e0f36424c8, content=有意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Sat Sep 05 09:24:00 CST 2015, time=2015-09-05, status=1, ipAttribution=)]
    2015-09-05 zhouanxiu

    有意义

    0

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