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Nanoscale Res Lett：银纳米粒子涂覆氧化石墨稀可更好的发挥抗菌作用

2018-05-02 MedSci MedSci原创

氧化石墨稀银抗菌
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针对耐药细菌的最有前途的方法之一是具有杀生物纳米颗粒和纳米复合材料的表面改性材料。在此，我们将银纳米粒子（Ag-NPs）涂布在氧化石墨烯（GO）的表面形成新的纳米复合材料作为一种多功能抗菌和抗真菌材料使用。 使用超声波技术涂布聚氨酯箔。通过分析细胞形态，使用PrestoBlue测定评估细胞活力，使用乳酸脱氢酶法分析细胞膜完整性，以及活性氧产生观察材料对革兰氏阴性菌（大肠杆菌），革兰氏阳性菌

针对耐药细菌的最有前途的方法之一是具有杀生物纳米颗粒和纳米复合材料的表面改性材料。在此，我们将银纳米粒子（Ag-NPs）涂布在氧化石墨烯（GO）的表面形成新的纳米复合材料作为一种多功能抗菌和抗真菌材料使用。

使用超声波技术涂布聚氨酯箔。通过分析细胞形态，使用PrestoBlue测定评估细胞活力，使用乳酸脱氢酶法分析细胞膜完整性，以及活性氧产生观察材料对革兰氏阴性菌（大肠杆菌），革兰氏阳性菌（金黄色葡萄球菌和表皮葡萄球菌）和致病性酵母（白色念珠菌）的毒性。

结果显示，与已被广泛用作抗菌剂的Ag-NPs和GO相比，本研究所制备的纳米复合材料对细菌和酵母细胞显示出更高的抗菌率。

原始出处：

Sławomir Jaworski, Mateusz Wierzbicki, et al., Graphene Oxide-Based Nanocomposites Decorated with Silver Nanoparticles as an Antibacterial Agent. Nanoscale Res Lett. 2018; 13: 116. doi:  10.1186/s11671-018-2533-2

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1772957, encodeId=20951e72957f4, content=<a href='/topic/show?id=89f3e742947' target=_blank style='color:#2F92EE;'>#纳米粒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77429, encryptionId=89f3e742947, topicName=纳米粒)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e8ae38449394, createdName=zjubiostat, createdTime=Tue Dec 25 15:54:00 CST 2018, time=2018-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1793661, encodeId=cea51e93661af, content=<a href='/topic/show?id=e40315955e3' target=_blank style='color:#2F92EE;'>#scale#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15955, encryptionId=e40315955e3, topicName=scale)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=68b666, createdName=zhangying8788, createdTime=Sun Feb 24 22:54:00 CST 2019, time=2019-02-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706971, encodeId=12251e06971e5, content=<a href='/topic/show?id=d2773359191' target=_blank style='color:#2F92EE;'>#化石#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33591, encryptionId=d2773359191, topicName=化石)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4d531331396, createdName=ms7899726347904398, createdTime=Sat Mar 16 13:54:00 CST 2019, time=2019-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1330704, encodeId=b3ea1330e042c, content=<a href='/topic/show?id=c6b455688d1' target=_blank style='color:#2F92EE;'>#抗菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55688, encryptionId=c6b455688d1, topicName=抗菌)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/1103841572/2898B09F0DA89357D0D54A725E611AC7/100, createdBy=fdd32500040, createdName=ms7899726347904398, createdTime=Fri May 04 07:54:00 CST 2018, time=2018-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1580634, encodeId=5f0f1580634e1, content=<a href='/topic/show?id=d4c6e7430be' target=_blank style='color:#2F92EE;'>#纳米粒子#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77430, encryptionId=d4c6e7430be, topicName=纳米粒子)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=eedc16636878, createdName=ms920641618706883, createdTime=Fri May 04 07:54:00 CST 2018, time=2018-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311679, encodeId=58ab3116e913, content=了解一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Thu May 03 19:20:12 CST 2018, time=2018-05-03, status=1, ipAttribution=)]
    2018-12-25 zjubiostat

    #纳米粒#

    0

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    2019-02-24 zhangying8788

    #scale#

    0

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    2019-03-16 ms7899726347904398

    #化石#

    0

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    2018-05-04 ms7899726347904398

    #抗菌#

    0

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    2018-05-04 ms920641618706883

    #纳米粒子#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1772957, encodeId=20951e72957f4, content=<a href='/topic/show?id=89f3e742947' target=_blank style='color:#2F92EE;'>#纳米粒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77429, encryptionId=89f3e742947, topicName=纳米粒)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e8ae38449394, createdName=zjubiostat, createdTime=Tue Dec 25 15:54:00 CST 2018, time=2018-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1793661, encodeId=cea51e93661af, content=<a href='/topic/show?id=e40315955e3' target=_blank style='color:#2F92EE;'>#scale#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15955, encryptionId=e40315955e3, topicName=scale)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=68b666, createdName=zhangying8788, createdTime=Sun Feb 24 22:54:00 CST 2019, time=2019-02-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706971, encodeId=12251e06971e5, content=<a href='/topic/show?id=d2773359191' target=_blank style='color:#2F92EE;'>#化石#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33591, encryptionId=d2773359191, topicName=化石)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4d531331396, createdName=ms7899726347904398, createdTime=Sat Mar 16 13:54:00 CST 2019, time=2019-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1330704, encodeId=b3ea1330e042c, content=<a href='/topic/show?id=c6b455688d1' target=_blank style='color:#2F92EE;'>#抗菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55688, encryptionId=c6b455688d1, topicName=抗菌)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/1103841572/2898B09F0DA89357D0D54A725E611AC7/100, createdBy=fdd32500040, createdName=ms7899726347904398, createdTime=Fri May 04 07:54:00 CST 2018, time=2018-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1580634, encodeId=5f0f1580634e1, content=<a href='/topic/show?id=d4c6e7430be' target=_blank style='color:#2F92EE;'>#纳米粒子#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77430, encryptionId=d4c6e7430be, topicName=纳米粒子)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=eedc16636878, createdName=ms920641618706883, createdTime=Fri May 04 07:54:00 CST 2018, time=2018-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311679, encodeId=58ab3116e913, content=了解一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Thu May 03 19:20:12 CST 2018, time=2018-05-03, status=1, ipAttribution=)]
    2018-05-03 wxl882001

    了解一下

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