J Endod:发育成熟牙齿牙髓再生治疗后根管内再生组织的定量评估

2020-03-26 lishiting MedSci原创

这篇研究的目的是通过磁共振成像技术(MRI)定量评估发育成熟牙齿采用2种不同大小的尖端预备方式实施牙髓再生治疗(REPs)后根管内的再生组织情况。

这篇研究的目的是通过磁共振成像技术(MRI)定量评估发育成熟牙齿采用2种不同大小的尖端预备方式实施牙髓再生治疗(REPs)后根管内的再生组织情况。

研究选取18颗上颌发育成熟的坏死并伴随根尖损伤的前牙作为实验对象。将牙齿随机分为2组。实验组和对照组均使用Protaper Next files (Dentsply Sirona, York, PA)行根管预备至X3和X5。随后实施REPs,并使用Biodentine (Septodont, Saint-Maur-des-Fossés, France)作为颈环界面处的生物材料。分别在术后3, 6和12个月,使用MRI检测2组根管中1/3和尖1/3处再生组织的信号强度(SI)。比较对侧健康牙齿和每个连续间隔之间的SI差异。在连续的时间段内对患牙进行临床检查、敏感度测试和数字化X线影像观察。采用Student t检验和Cochran检验对数据进行统计学分析,显著性水平设置为P ≤ .05。

结果显示,所有18颗牙齿均无症状并且根尖损伤愈合。SI检测结果显示,术后12个月治疗牙齿内的再生组织和对侧健康牙齿之间的SI无显著性差异。2组在术后12个月均有超过60%的牙齿重新获得牙髓活力。

结论:发育成熟牙齿中采用REPs能够再生有活力的牙髓样组织,并且根尖直径的大小并不会明显影响治疗效果。MRI是一种非侵袭性的能够定量评估再生组织的有效方法。

原始出处

Noha Mohamed El-Kateb, Rania Noaman El-Backly, et al. Quantitative Assessment of Intracanal Regenerated Tissues After Regenerative Endodontic Procedures in Mature Teeth Using Magnetic Resonance Imaging: A Randomized Controlled Clinical Trial. J Endod 2020 Mar 12[Online ahead of print]

 

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    2021-02-01 jxrzshh
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    2020-03-28 neurowu
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    2020-03-28 zhouqu_8
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J Endod:坏死牙髓伴随尖周暗影的发育成熟牙齿的牙髓再生治疗:一项初步临床随机试验

这篇初步研究的目的是为了比较牙髓再生疗法(REPs)和常规根管治疗(CRCT)对牙髓坏死伴随根尖周暗影的发育成熟牙齿的临床和放射性影像疗效。

J Endod:2颗经过牙髓再生治疗的未发育完成牙齿的综合特征

牙髓-牙本质复合体的再生是牙髓再生治疗(REPs)的一个次级目标。对拔除已行REPs的人牙齿的组织学结果发现存在修复性组织形成。然而,还缺少准确的特征描述来鉴定REPs后所形成组织的真实本质。