Journal of Neuropsychology:两种相似但不同的退行性疾病的新发现

2014-10-14 佚名 生物谷

近日研究发现,墨尔本大学的研究人员已经鉴定出两种疾病似乎存在类似的疾病表征方式,但实际上这两种疾病的本质是完全不同的。进行性核上麻痹(PSP)和帕金森病(PD)有相同的临床症状,但除此之外的部分仍难以区分。 然而,有关该主题的论文首次发表在《神经心理学》(英国心理学会刊物)杂志上,该文表明PSP患者比那些患早期帕金森病的患者具有更严重和广泛的认知障碍。 研究表明,具有严重和广泛认知障碍的P

近日研究发现,墨尔本大学的研究人员已经鉴定出两种疾病似乎存在类似的疾病表征方式,但实际上这两种疾病的本质是完全不同的。进行性核上麻痹(PSP)和帕金森病(PD)有相同的临床症状,但除此之外的部分仍难以区分。

然而,有关该主题的论文首次发表在《神经心理学》(英国心理学会刊物)杂志上,该文表明PSP患者比那些患早期帕金森病的患者具有更严重和广泛的认知障碍。

研究表明,具有严重和广泛认知障碍的PSP患者比PD患者拥有较为高级的能力如规划能力、抽象思维能力、记忆再现能力。

研究员Young-Eun Claire Lee博士说这两个疾病病症是如此相似以至于在某些情况下PSP患者因为疾病的主要临床表征而无法确诊此病。

“PD和PSP是神经退行性疾病的两种最常见的形式,这两种疾病导致病人失去平衡和行动退化。”李博士说。

“区分这些差异是很具有挑战性的,因为大多数PSP患者没有独特的症状,比如瘫痪或眼部肌肉萎缩,到疾病发病后期眼部肌肉会不断下垂。”她说。

虽然这项研究样本很小,但研究结果表明,认知现象可以帮助医生在疾病早期阶段进行鉴别诊断。。

目前还没有较好的治疗PSP的方法。

原始出处

Young-Eun C. Lee1, David R. Williams2,3 andJacqueline F. I. Anderson1,4,* Frontal deficits differentiate progressive supranuclear palsy from Parkinson's disease.Journal of Neuropsychology.2014

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    2014-12-19 rosa00tong

    PSP患者比那些患早期帕金森病的患者具有更严重和广泛的认知障碍。

    0

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