Clin Pharm Ther：外用聚维酮碘溶液能够导致血糖测量值高估

2016-08-19 佚名生物谷

血液中的糖分称为血糖，绝大多数情况下都是葡萄糖（英文简写Glu）。体内各组织细胞活动所需的能量大部分来自葡萄糖，所以血糖必须保持一定的水平才能维持体内各器官和组织的需要。根据一项病例报告，使用外用碘溶液能够导致血糖测量值高估。相关研究结果于2016年8月8日在线发表在Journal of Clinical Pharmacy and Therapeutics期刊上，论文标题为“Probable

血液中的糖分称为血糖，绝大多数情况下都是葡萄糖（英文简写Glu）。体内各组织细胞活动所需的能量大部分来自葡萄糖，所以血糖必须保持一定的水平才能维持体内各器官和组织的需要。

根据一项病例报告，使用外用碘溶液能够导致血糖测量值高估。相关研究结果于2016年8月8日在线发表在Journal of Clinical Pharmacy and Therapeutics期刊上，论文标题为“Probable glucometer interference caused by topical iodine solution test site preparation”。

来自美国俄亥俄州哥伦布市迦密山西医院的A.M. Lipshutz博士和来自美国北卡罗来纳大学教堂山分校的Emily M. Hawes博士发布了一篇针对一名28岁华裔孕妇的外用碘溶液与即时检测血糖仪之间存在临床上有意义的很可能发生的药物-设备相互作用的病例报告。一诊断患上妊娠糖尿病后，这名孕妇就被要求开始进行每天4次自我监控的血糖测试。她觉得这些测量值是不准确的：在5到10分钟内，在107 mg/dL到160 mg/dL之间变化。在拜访诊所访问一名医师后，经证实，她的测量方法是正确的。

通过与这名病人进行深入的交谈，研究人员发现在检测血糖之前，她已将10%的聚维酮碘溶液施用在测试位点上。她被要求在检测之前用肥皂洗手，结果导致利用两种即时血糖检测设备的测量值更加相一致。采用合适的洗手方法后，她在测量时就不再存在异常的血糖读数值。在停止使用碘液后，所有的测量值在整个怀孕期间都保持在她的目标值之下。

论文作者们写道，“在存在异常的或变化的血糖测量值的病人体内，血糖仪提供商应当研究是否存在不正确的测试方法。”

原始出处

A. M. Lipshutz and E. M. Hawes.Probable glucometer interference caused by topical iodine solution test site preparation.J Clin Pharm Ther.2016

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2017-03-08 jj000001

#Pharm#

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2016-08-26 李东泽

这篇资讯写的真好，带给我们新知识，启发新思维，不论是科研还是临床工作都有很大的帮助。。。

56 0
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2016-08-26 李东泽

这篇资讯写的真好，带给我们新知识，启发新思维，不论是科研还是临床工作都有很大的帮助。。。

42 0
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level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Tue Aug 23 09:00:00 CST 2016, time=2016-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=101945, encodeId=a95c10194539, content=共同进步！, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160817/IMG57B3C3F6DC2FD8753.jpg, createdBy=81321934679, createdName=1e0d99ddm02(暂无匿称), createdTime=Sun Aug 21 13:36:00 CST 2016, time=2016-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=101291, encodeId=f17e10129103, content=阅读了。, beContent=null, objectType=article, channel=null, 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beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLMzGpMQ8w4I7FpiblCXNcmI6O7TDINutbaicEUpoYFR1rWqn3kTbulfMhT0iaPFurLz2ddEcWe3BiciaQ/0, createdBy=5f6e1724878, createdName=136****0753赵, createdTime=Fri Aug 19 22:53:00 CST 2016, time=2016-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=101087, encodeId=db3910108edc, content=好好学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=75c61925532, createdName=rookieblue, createdTime=Fri Aug 19 16:38:00 CST 2016, time=2016-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=101010, encodeId=736a10101085, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLMzGpMQ8w4I7FpiblCXNcmI6O7TDINutbaicEUpoYFR1rWqn3kTbulfMhT0iaPFurLz2ddEcWe3BiciaQ/0, createdBy=5f6e1724878, createdName=136****0753赵, createdTime=Fri Aug 19 16:05:00 CST 2016, time=2016-08-19, status=1, ipAttribution=)]
2016-08-23 刘煜

阅读了。

0 0
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2016-08-21 1e0d99ddm02(暂无匿称)

共同进步！

47 0
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objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLMzGpMQ8w4I7FpiblCXNcmI6O7TDINutbaicEUpoYFR1rWqn3kTbulfMhT0iaPFurLz2ddEcWe3BiciaQ/0, createdBy=5f6e1724878, createdName=136****0753赵, createdTime=Fri Aug 19 16:05:00 CST 2016, time=2016-08-19, status=1, ipAttribution=)]
2016-08-20 刘煜

阅读了。

52 0
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2016-08-19 136****0753赵

值得学习

17 0
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2016-08-19 136****0753赵

值得学习

0 0
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2016-08-19 rookieblue

好好学习一下

21 0
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objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLMzGpMQ8w4I7FpiblCXNcmI6O7TDINutbaicEUpoYFR1rWqn3kTbulfMhT0iaPFurLz2ddEcWe3BiciaQ/0, createdBy=5f6e1724878, createdName=136****0753赵, createdTime=Fri Aug 19 16:05:00 CST 2016, time=2016-08-19, status=1, ipAttribution=)]
2016-08-19 136****0753赵

值得学习

21 0