J Clin Periodontol:HFE血色病患者牙周状况和血清生物标志物水平之间的关系

2017-09-16 MedSci MedSci原创

调查HFE血色素沉着症患者牙周状态与血清生物标志物的关系。

调查HFE血色素沉着症患者牙周状态与血清生物标志物的关系。

材料与方法:该临床病例系列包括84例HFE-C282Y纯合子患者。使用临床附着水平,探诊深度,牙龈出血指数,可见菌斑指数和牙龈指数进行牙周评估。从医疗记录中收集铁代谢的血清标志物。研究铁负荷的血清生物标志物与牙周炎的严重程度之间的关系。

结果:研究人群由47名男性和37名女性组成,在雷恩大学医院肝病科进行了常规治疗。所有患者均出现牙周炎(轻度:n = 1,中度:n = 37,重度:n = 46)。转铁蛋白饱和度> 45%与牙周炎的严重程度之间存在正相关(调整的优势比= 5.49,p = .002)。

结论:重度牙周炎与HFE相关遗传性血色素沉着症患者的铁负荷程度相关。口腔检查应纳入所有这些患者的初步评估。

原始出处:

Vincent Meuric, Fabrice Laine, Emile Boyer, et al. Periodontal status and serum biomarker levels in HFE haemochromatosis patients. A case-series study. Journal of Clinical Periodontology. 2017 September. doi: 10.1111/jcpe.12760

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    2018-07-02 feather89
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    2017-09-18 liuyong2982
  5. 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  8. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=d41c2055892, createdName=184****9840, createdTime=Sat Sep 16 23:41:08 CST 2017, time=2017-09-16, status=1, ipAttribution=)]
    2017-09-17 执着追梦

    学习.谢谢分享

    0

  9. 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    2017-09-16 130****4638

    学习了谢谢分享

    0

  10. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=d41c2055892, createdName=184****9840, createdTime=Sat Sep 16 23:41:08 CST 2017, time=2017-09-16, status=1, ipAttribution=)]
    2017-09-16 184****9840

    学习了谢谢分享

    0

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伴放线放线杆菌参与了口腔和全身感染,并与,如牙周炎和心内膜炎侵袭形式有关。cagE基因编码由伴放线放线杆菌表达的≈39kDa的假定的外毒素。cagE的保存水平和牙周病可能的意义尚未彻底调查。在本研究中,调查了cagE基因作为诊断标记物的作用。

J Periodontal Res:低水平激光治疗辅助牙周非手术对于吸烟和非吸烟慢性牙周炎患者的治疗:半口,随机对照研究

本研究旨在调查低水平激光治疗(LLLT)作为吸烟和非吸烟慢性牙周炎患者的刮治和根面平整(SRP)治疗的辅助作用。