Eur Heart J:诊所血压或动态血压能预测心血管风险吗?

2017-12-26 安雅晶 环球医学

2017年发表在《Eur Heart J》的一项由丹麦科学家进行的研究,考察了诊所血压或动态血压预测心血管事件的准确性。

2017年发表在《Eur Heart J》的一项由丹麦科学家进行的研究,考察了诊所血压或动态血压预测心血管事件的准确性。

目的:确定(1)24 h动态血压相对于诊所血压;(2)夜间动态血压相对于日间动态血压对10年特定人群致命或非致命心血管事件绝对风险的预测作用。

方法和结果:纳入心血管结局相关动态血压监测国际数据库中7927例受试者。使用特定原因Cox回归,预测10年特定人群致命或非致命心血管事件绝对风险。通过时间依赖受者特性曲线下面积(AUC),描述10年结局。比较诊所血压和动态血压时,没有观察到预测风险存在差异。心血管死亡率的10年风险(第1个;第3个四分位数)中位差异为?0.01%(?0.3%;0.1%),心血管事件的10年风险中位差异为?0.1%(?1.1%;0.5%)。心血管死亡率的AUC差异(95%置信区间[CI])为0.65%(0.22%~1.08%),心血管事件的AUC差异为1.33%(0.83%~1.84%)。比较白天和夜间血压,心血管死亡的10年风险平均差异为0.002%(?0.1%;0.1%),心血管事件的10年风险平均差异为?0.01%(?0.5%;0.2%)。心血管死亡的AUC差异为0.10%(?0.08~0.29%),心血管事件的AUC差异为0.15%(?0.06~0.35%)。

结论:动态血压获得的10年预测与诊所血压的预测相似。夜间血压不能改善白天测量的10年预测。对于健康人群而言,诊所血压可以实现心血管风险足够的预测准确性。

原始出处:
Mortensen RN, Gerds TA, Jeppesen JL,et al.Office blood pressure or ambulatory blood pressure for the prediction of cardiovascular events.Eur Heart J. 2017 Nov 21;38(44):3296-3304. doi: 10.1093/eurheartj/ehx464.

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    2017-12-28 ycmayy
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    2017-12-28 zhaojie88
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    2017-12-28 slcumt
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    2017-12-26 131****1460

    学习了受益匪浅

    0

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    2017-12-26 changjiu

    学习一下谢谢

    0