Eur Raidol:外周小血管病患者福音--光声体层成像在显示外周血管及微血管对温度刺激舒缩反应的价值

2017-11-16 shaosai MedSci原创

光声成像是近年来发展起来的一种无损医学成像方法,它结合了纯光学成像的高对比度特性和纯超声成像的高穿透深度特性,可以提供高分辨率和高对比度的组织成像。本研究旨在验证新型光声体层成像(PAI)系统是否有能够清晰显示外周血管及微血管循环对温度刺激变化的价值,并将结果发表在Eur Raidol上。

光声成像是近年来发展起来的一种无损医学成像方法,它结合了纯光学成像的高对比度特性和纯超声成像的高穿透深度特性,可以提供高分辨率和高对比度的组织成像。本研究旨在验证新型光声体层成像(PAI)系统是否有能够清晰显示外周血管及微血管循环对温度刺激变化的价值,并将结果发表在Eur Raidol上。

本研究共纳入了8名行足背动脉PAI的志愿者及13名行食指指尖PAI的志愿者。手指图像采集是在放入温水或冷水后进行采集的,以便促进血管的舒张或收缩。PAI设备采用Fabry-Perot干涉仪的超声感受器及30-Hz 750-nm脉冲式激发激光。在90秒内获取14 × 14 × 14-mm大小的容积图像。主观及定量评价图像来验证是否PAI能够显示冷温度诱导的血管收缩。测量血管的半极大处全宽度(FWHM)。

结果为,所有受试者的指尖血管均能显示,平均FWHM为125μm。两名放射科医生利用PAI成功地识别了收缩的指尖毛细血管床,准确率为100%(95% CI 77.2-100.0%, p < 0.001)。显示血管信号的体素数量再置入冷水后要明显减小(冷水:5263个;热水:363,470 个, p < 0.001)。足背动脉在7/8的受试者中能够观察到(87.5%)。

本研究表明,PAI能够快速地对外周肢体血管及微血管结构进行容积高分辨率成像,并能够对由温度刺激诱导的血管舒缩运动进行显示。

原始出处:


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createdBy=64bb23195917, createdName=Luyuxie_17, createdTime=Thu Aug 09 03:46:00 CST 2018, time=2018-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2071085, encodeId=9ee620e1085eb, content=<a href='/topic/show?id=5dc442829f8' target=_blank style='color:#2F92EE;'>#外周血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42829, encryptionId=5dc442829f8, topicName=外周血管)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6e43278, createdName=yangjxjc, createdTime=Sat Oct 13 07:46:00 CST 2018, time=2018-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1703503, encodeId=d8af1e03503fa, content=<a href='/topic/show?id=327e9425fc' target=_blank style='color:#2F92EE;'>#IDO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9425, encryptionId=327e9425fc, topicName=IDO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3e3a30514791, createdName=tongyongming, createdTime=Wed Feb 21 02:46:00 CST 2018, time=2018-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=282896, encodeId=3bba28289670, content=多学习才能避免失误.给病人带来实惠, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sun Jan 28 15:37:51 CST 2018, time=2018-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=271035, encodeId=6ba92e103560, content=好资料学习了好资料!, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Wed Dec 20 23:35:06 CST 2017, time=2017-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2033854, encodeId=3fb4203385494, content=<a href='/topic/show?id=852b216824' target=_blank style='color:#2F92EE;'>#AID#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2168, encryptionId=852b216824, topicName=AID)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1072181, createdName=wjywjy, createdTime=Tue Aug 14 16:46:00 CST 2018, time=2018-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1365330, encodeId=731d13653304d, content=<a href='/topic/show?id=2a2150e76fd' target=_blank style='color:#2F92EE;'>#微血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50776, encryptionId=2a2150e76fd, topicName=微血管)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=669d219, createdName=mgqwxj, createdTime=Sat Nov 18 06:46:00 CST 2017, time=2017-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1578532, encodeId=4ddf15e85329c, content=<a href='/topic/show?id=fd724282021' target=_blank style='color:#2F92EE;'>#外周血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42820, encryptionId=fd724282021, topicName=外周血)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a31916414168, createdName=ms3994565386320060, createdTime=Sat Nov 18 06:46:00 CST 2017, time=2017-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261798, encodeId=3f76261e98bf, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5KiblTyxD95ExbzUoCVcRuhPibXboL28wicFMTXUhCA0RWCyQZYC5Na3ap7CxjialMkB50VEJ0XToQQTC/0, createdBy=470c1945776, createdName=方舒, createdTime=Thu Nov 16 20:59:18 CST 2017, time=2017-11-16, status=1, ipAttribution=)]
    2018-02-21 tongyongming
  5. 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href='/topic/show?id=2a2150e76fd' target=_blank style='color:#2F92EE;'>#微血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50776, encryptionId=2a2150e76fd, topicName=微血管)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=669d219, createdName=mgqwxj, createdTime=Sat Nov 18 06:46:00 CST 2017, time=2017-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1578532, encodeId=4ddf15e85329c, content=<a href='/topic/show?id=fd724282021' target=_blank style='color:#2F92EE;'>#外周血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42820, encryptionId=fd724282021, topicName=外周血)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a31916414168, createdName=ms3994565386320060, createdTime=Sat Nov 18 06:46:00 CST 2017, time=2017-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261798, encodeId=3f76261e98bf, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5KiblTyxD95ExbzUoCVcRuhPibXboL28wicFMTXUhCA0RWCyQZYC5Na3ap7CxjialMkB50VEJ0XToQQTC/0, createdBy=470c1945776, createdName=方舒, createdTime=Thu Nov 16 20:59:18 CST 2017, time=2017-11-16, status=1, ipAttribution=)]
    2018-01-28 虈亣靌

    多学习才能避免失误.给病人带来实惠

    0

  6. 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href='/topic/show?id=2a2150e76fd' target=_blank style='color:#2F92EE;'>#微血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50776, encryptionId=2a2150e76fd, topicName=微血管)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=669d219, createdName=mgqwxj, createdTime=Sat Nov 18 06:46:00 CST 2017, time=2017-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1578532, encodeId=4ddf15e85329c, content=<a href='/topic/show?id=fd724282021' target=_blank style='color:#2F92EE;'>#外周血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42820, encryptionId=fd724282021, topicName=外周血)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a31916414168, createdName=ms3994565386320060, createdTime=Sat Nov 18 06:46:00 CST 2017, time=2017-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261798, encodeId=3f76261e98bf, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5KiblTyxD95ExbzUoCVcRuhPibXboL28wicFMTXUhCA0RWCyQZYC5Na3ap7CxjialMkB50VEJ0XToQQTC/0, createdBy=470c1945776, createdName=方舒, createdTime=Thu Nov 16 20:59:18 CST 2017, time=2017-11-16, status=1, ipAttribution=)]
    2017-12-20 虈亣靌

    好资料学习了好资料!

    0

  7. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261798, encodeId=3f76261e98bf, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5KiblTyxD95ExbzUoCVcRuhPibXboL28wicFMTXUhCA0RWCyQZYC5Na3ap7CxjialMkB50VEJ0XToQQTC/0, createdBy=470c1945776, createdName=方舒, createdTime=Thu Nov 16 20:59:18 CST 2017, time=2017-11-16, status=1, ipAttribution=)]
    2018-08-14 wjywjy
  8. 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    2017-11-18 mgqwxj
  9. 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    2017-11-16 方舒

    学习

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