J Gastroenterol:Cine-MRI评估假性肠梗阻

2016-08-28 Moon 译 MedSci原创

假性肠梗阻是由于神经抑制、毒素刺激或肠壁平滑肌本身的病变,所致肠壁肌肉运动功能紊乱。临床具有肠梗阻的症状和体征,但无肠内外机械性肠梗阻因素存在。按病程有急性和慢性之分,麻痹性肠梗阻和痉挛性肠梗阻属于急性假性肠梗阻,慢性假性肠梗阻有原发性和继发性两种。 慢性假性肠梗阻(CIPO)比较罕见,会导致极其严重的消化道功能紊乱,其临床病程和严重性变化性很大。我们使用cine-MRI(视频动态MRI)评

假性肠梗阻是由于神经抑制、毒素刺激或肠壁平滑肌本身的病变,所致肠壁肌肉运动功能紊乱。临床具有肠梗阻的症状和体征,但无肠内外机械性肠梗阻因素存在。按病程有急性和慢性之分,麻痹性肠梗阻和痉挛性肠梗阻属于急性假性肠梗阻,慢性假性肠梗阻有原发性和继发性两种。

慢性假性肠梗阻(CIPO)比较罕见,会导致极其严重的消化道功能紊乱,其临床病程和严重性变化性很大。我们使用cine-MRI(视频动态MRI)评估CIPO患者持续的小肠蠕动,结合患者的临床特征,评价这种顽固性疾病患者进行cine-MRI的临床意义。

根据医疗记录识别了131名CIPO患者,33名(22名女性,11名男性,年龄范围16-79年)符合纳入标准,接受了cine-MRI。与健康志愿者比较了平均管腔直径(MLD)、压缩比(CR)和收缩周期(CC)等参数。此外也评价了CIPO患者的临床治疗效果。

中位随访时间为25.2个月(范围1-65月)。33名CIPO患者中23(70%)例表现出明显不安的小肠蠕动 ,10(30%)例患者则没有这种情况。有小肠蠕动受损的患者与没有的患者相比较,需要静脉营养的患者比例显著较高(p = 0.03),平均血清白蛋白水平显著降低(p = 0.04)。虽然10例没有异常小肠蠕动的患者其cine-MRI和CT结果在正常范围内,但是与健康志愿者相比,MLD和CR仍有区别。

结果表明,Cine-MRI预测CIPO患者严重的临床特征是有用的,并且可以检测到CT观察不到的轻微收缩性受损。

原始出处:

Fuyuki A.et al. Clinical importance of cine-MRI assessment of small bowel motility in patients with chronic intestinal pseudo-obstruction: a retrospective study of 33 patients. J Gastroenterol. 2016 August 22.

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    2016-11-04 kalseyzl
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    2016-12-05 许安
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    2016-09-13 lhl629

    努力学习。。。

    0

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    2016-09-05 李东泽

    很好,不错,以后会多学习

    0

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