Pediatr Crit Care Me:体外膜肺治疗的观察性研究

2014-12-22 MedSci MedSci原创译

近日,阿肯色医科大学医学院的Fiser医生等对儿童医院的儿科、心血管科室、新生儿ICU科室等进行了一项体外膜肺(ECMO)治疗的观察性研究,该研究纳入了2010年1月1日至12月31日所有ECMO支持的患儿。结果发现,有45名患儿使用了ECMO治疗。ECMO治疗期间患儿的失血量平均为75ml/kg。一共进行了617次输血,ECMO支持期间有心脏病的患儿其平均红细胞含量为254ml/kg,无心脏病的

近日,阿肯色医科大学医学院的Fiser医生等对儿童医院的儿科、心血管科室、新生儿ICU科室等进行了一项体外膜肺(ECMO)治疗的观察性研究,该研究纳入了2010年1月1日至12月31日所有ECMO支持的患儿。结果发现,有45名患儿使用了ECMO治疗。ECMO治疗期间患儿的失血量平均为75ml/kg。一共进行了617次输血,ECMO支持期间有心脏病的患儿其平均红细胞含量为254ml/kg,无心脏病的患儿其平均红细胞含量为267ml/kg。在患心脏病的儿童中,ECMO治疗时需要的平均红细胞为131ml/kg,而无心脏病的患儿平均为80ml/kg。心外科患者输血量最多,为529ml/kg。ECMO治疗期间的平均血细胞比容为37%,有或无心脏病的患儿之间没有差别。ECMO支持治疗的患儿平均接受10.9个单位的供者红细胞。近红外光谱发现,大部分输血没有SvO2或脑内血液氧合的显著改变。只有5%的输血患儿的SvO2升高了5%,但是只有9%的患儿其脑内血氧饱和度升高了5。大部分输血前大部分患儿的SvO2高于70%。结果表明,用ECMO支持治疗的患儿由于失血导致的轻度贫血而需要输入大量的红细胞。SvO

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    2015-05-05 feather89
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