Materials:种植体周围炎感染植体是否还可以重获骨结合?

2020-03-13 MedSci原创 MedSci原创

钛具有出色的生物相容性和非凡的机械性能,因此被用作牙科植入物的材料。种植体周围炎感染的种植体可以再次进行清洁处理以重获骨结合。最佳的表面特性(例如粗糙度和润湿性)对细胞粘附有重要影响。本研究旨在评估成

钛具有出色的生物相容性和非凡的机械性能,因此被用作牙科植入物的材料。种植体周围炎感染的种植体可以再次进行清洁处理以重获骨结合。最佳的表面特性(例如粗糙度和润湿性)对细胞粘附有重要影响。本研究旨在评估成骨细胞在反复清洗的纳米结构钛样品表面上的粘附和增殖。

 

将人成骨样细胞MG-63接种在纳米结构的钛标本上,该标本由通过等通道角压制成的棒制成。进行表面表征,测量粗糙度和润湿性。评估接种后2小时后的细胞粘附以及48小时后的细胞增殖。

 

结果显示,钛表面的这种反复清洁降低了细胞粘附以及增殖。这主要与钛的表面特性(如润湿性,粗糙度和形貌)发生变化有关。很难确定导致这些事件的因素,因此需要进一步调查。但是,即使经过几轮反复清洗,仍观察到细胞一定的粘附和扩散速率。因此,通过原位清洁来保存失败的植入物是有希望的。

 

原始出处:

 

Vaclav BabuskaJana Kolaja Dobra, et al., Repeated Exposure of Nanostructured Titanium to Osteoblasts with Respect to Peri-Implantitis. Materials (Basel). 2020 Feb; 13(3): 697.

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    2021-01-19 huangdf
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    2020-03-16 12168424m28(暂无昵称)

    学习了

    0

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