Neurology:长期服用ω-3多不饱和脂肪酸有助于改善进展性糖尿病感觉神经病变

2017-05-18 zhangfan MedSci原创

长期服用ω-3多不饱和脂肪酸有助于改善进展性糖尿病感觉神经病变,是进展性糖尿病感觉神经病变改善的IV证据

近日研究人员就ω-3多不饱和脂肪酸(ω- 3 PUFA)对I型糖尿病(T1DM)引发的进展性感觉神经病变(DSP)的影响开展研究。

I型糖尿病进展性感觉神经病变患者开展为期1年的无对照单臂研究,每天服用750mg的二十碳五烯酸,560mg的鲱油酸以及1020mg的二十二碳六烯酸。主要终点体内角膜共焦显微镜测定的角膜神经纤维长度(CNFL)的年变化,次要终点是感官和神经传导测试变化。

共40名参与者,其中53%为女性,平均年龄48岁,平均体重指数28.1。基线时,有23名参与者患有进展性糖尿病感觉神经病变,17名糖尿病患者无神经病变。基线CNFL为8.3±2.9 mm/mm2,12个月后增长29%至10.1± 3.7 mm/mm2。神经传导或感觉功能无变化。

研究认为长期服用ω-3多不饱和脂肪酸有助于改善进展性糖尿病感觉神经病变,是进展性糖尿病感觉神经病变改善的IV证据。

原始出处:

Evan J.H. Lewis et al. Effect of omega-3 supplementation on neuropathy in type 1 diabetes. Neurology. May 17 2017.

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  5. 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  6. 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    2017-07-11 yinhl1978
  7. 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  9. 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    2017-05-20 axin012
  10. 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偶尔多吃半碗米、来个炸鸡…糖尿病不能这样放松

在门诊中常会有糖友问,偶尔多吃半碗米饭行吗?偶尔吃个炸鸡行吗?这么多的偶尔加起来,你的血糖还好吗?糖尿病的治疗是长期的过程,部分患者认为偶尔让自己“放松”是可以的,却不知隐患都是在这时埋下的。偶尔一次:多吃了一碗米饭专家点评:米饭易吸收,容易导致血糖波动,所以要控制好每天进食米饭的量。偶尔一次:胰岛素注射针头使用2次专家点评:注射针头2次使用时,针头中残留的药液会影响剂量的准确性;针头内残留的胰岛

关于糖尿病的四个误解

世界卫生组织估计全球糖尿病患者为4.22亿。在1980至2014年间,糖尿病患者的数量几乎翻了一倍。尽管这种疾病非常普遍,但人们对它的误解也很多。以下是关于糖尿病的常见误解。1. 糖尿病是单纯的胰腺问题糖尿病的确会影响胰腺,但是它不仅仅会影响脖子以下的身体部分。如果我们采取这种观点,那么就会忽略患糖尿病导致的心理影响。这是一个大问题。由于糖尿病是一种长期的健康问题,所以糖尿病患者更容易产生抑郁问题

Diabetes Obes Metab:对于亚洲2型糖尿病患者 这种药物联合治疗安全有效

2017年5月,发表在《Diabetes Obes Metab》的一项由中国、韩国、马来西亚和英国科学家进行的研究,考察了亚洲2型糖尿病患者阿格列汀联合二甲双胍混合剂量联合治疗的有效性和安全性。

Diabetes Obes Metab:基线HbA1c水平和低血糖与不良心血管事件有多大关联?

2017年5月,发表在《Diabetes Obes Metab》的一项研究调查了糖化血红蛋白(HbA1c)与低血糖与主要不良心血管事件(MACE)风险之间的关联。研究结果显示,基线HbA1c水平或治疗1个月后HbA1c水平与MACE水平无关。低血糖事件和严重低血糖与MACE相关。

Diabetes Obes Metab:糖尿病合并高血压计步数带来的益处堪比吃药

近年来,计步数作为一种作追踪运动情况的工具非常流行。已经有研究结果支持将计步数融合到心血管代谢高风险个体的临床管理当中。2017年5月,发表在《Diabetes Obes Metab》的随机对照研究考察了医生处方计步和监测对2型糖尿病合并高血压患者的作用。