JAMA Oncol:避孕药可大大降低女性癌症发病率!

2018-01-20 Juka 转化医学网

避孕药的使用可以降低卵巢癌的发生率。而在近期,一项超10万人的研究不仅坐实了这个结论,并且研究结果十分喜人:哪怕是吸烟和肥胖患者,服用避孕药依旧可以降低卵巢癌的发生率!

避孕药的使用可以降低卵巢癌的发生率。而在近期,一项超10万人的研究不仅坐实了这个结论,并且研究结果十分喜人:哪怕是吸烟和肥胖患者,服用避孕药依旧可以降低卵巢癌的发生率!

众所周知,避孕药可以降低卵巢癌的发生率。而根据最近美国国立研究院的研究显示:避孕药的好处可能并不仅仅如此!

癌症研究所流行病学家Carol Michels领导的研究小组经过长期的研究发现:长期服用避孕药可以降低卵巢癌和子宫内膜癌两种癌症的发生率,而且这种情况“在整个健康行为中基本一致”——也就是说,不论患者是不是采取相对健康的生活模式,这个结果都基本不变。

这项研究于1月18日发表在《JAMA Oncology》上,题目名为“Modification of the Associations Between Duration of Oral Contraceptive Use and Ovarian, Endometrial, Breast, and Colorectal Cancers”。这篇文章研究了1995年到2011年总计超过10万的女性,研究发现:口服避孕药可以降低卵巢癌风险高达40%!

在中美癌症数据中,卵巢癌和子宫内膜癌都极大的危害了女性健康。根据美国癌症协会的统计,到2018年,被确诊为卵巢癌的患者将超过22000人,而这个疾病将夺去超过14000人的性命;而子宫内膜癌更加常见,在今年,确证患者超过63000人,将有11000死于这种癌症。

在本次研究中,研究人员发现:服用10年甚至以上避孕药的女性卵巢癌的发病风险降低了40%。而在调查分析中发现,这种益处是不分是否吸烟以及肥胖与否,在所有的人群中获益率是一致的。

而对于子宫内膜癌,研究人员发现避孕药对于那些抽烟和肥胖的女性来说获益更大。吸烟妇女口服避孕药时子宫内膜癌的风险下降了53%;而肥胖女性获益更大,子宫内膜癌的风险降低了64%。

在此项研究中,长期服用避孕药并没有降低女性乳腺癌结直肠癌的发病率。

避孕药如何起到防护作用的呢?

根据Carol Michels给出的说法:因为长期口服避孕药可以补充女性激素中的孕激素,长期使用之后,可能会降低女性在月经期间暴露在“雌二醇”的风险。而对于女性来说,雌二醇和癌症的增加相关。

由此,我们不得不提一下在2017年2月8日发表在《美国产科和妇科学杂志》上的一篇文章,这是全世界研究时间最长的一篇研究:这篇文章跨度达44年,共计研究了46022名女性。由于时间之长、研究之广,其最终使得科学家可以通过数据来证实避孕药和癌症之间的关系:

在这项研究中,长期使用避孕药的女性,相较于那些从未使用过避孕药的女性:总体终生癌症风险降低56.1%——主要降低的癌症包括结肠癌(81%)、子宫内膜癌(66%)、卵巢癌(67%)、淋巴血液系统癌症(74%)。而且在这项研究中,发现避孕药的保护作用可以长达30年!

而今发表在《JAMA Oncology》的这篇文章也证实了避孕药的强大抗癌作用。但是很不幸的,在中国,避孕药是一个难以启齿的文字组合。

中国的性教育远远落后于世界,这是公认的事实。而由于思想的保守型,中国的性教育一向缺缺,近些年来频频被曝光的女性性侵案件让大众震惊不已。对于正常的性知识都难以正确的铺展开来,所以对于避孕药这样一个事后药物,很多人并不能够正确的认识起作用。

在中国,2013年卫计委发布的人流数目为1300万,到如今,这个数目只能说只增不减,其中原因不说都已明了。

当然我们并不鼓励女性使用避孕药来进行癌症的防治,但是至少:长期使用避孕药对于人体的健康益处是大于害处的。

最后,避孕药确实是有益的,但是如果真正的爱护女性,请做好防护措施。1300万人流的背后,不仅有1300万个受伤的女性和家庭,还有1300万个不负责任的男性。

原始出处:


2.Lisa Iversen,et al.Lifetime cancer risk and combined oral contraceptives: the Royal College of General Practitioners’ Oral Contraception Study.Am J Obstet Gynecol.June 2017Volume 216, Issue 6, Pages 580.e1–580.e9.

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    2018-03-28 minlingfeng
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    2018-01-28 明崖

    学习了.有用.期望继续研究

    0

  4. 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    2018-01-23 jihuaijun1112

    学习学习学习

    0

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    2018-01-21 1e0e5697m83(暂无匿称)

    henhao

    0

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createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Sat Jan 20 20:41:12 CST 2018, time=2018-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=280447, encodeId=237928044ec3, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Sat Jan 20 20:08:31 CST 2018, time=2018-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=280429, encodeId=446a28042962, content=避孕药的使用可以降低卵巢癌的发生率.而在近期.一项超10万人的研究不仅坐实了这个结论.并且研究结果十分喜人:哪怕是吸烟和肥胖患者.服用避孕药依旧可以降低卵巢癌的发生率!, beContent=null, objectType=article, channel=null, level=null, likeNumber=17, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Sat Jan 20 19:05:02 CST 2018, time=2018-01-20, status=1, ipAttribution=)]
    2018-01-21 1e0e5a1fm42(暂无匿称)

    henhao

    0

  7. 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objectType=article, channel=null, level=null, likeNumber=17, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Sat Jan 20 19:05:02 CST 2018, time=2018-01-20, status=1, ipAttribution=)]
    2018-01-21 thlabcde

    好资料学习了!

    0

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    2018-01-20 戒馋,懒,贪

    谢谢分享学习了

    0

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    2018-01-20 131****1460

    学习了受益匪浅

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    2018-01-20 有备才能无患

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    0

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