Am J Cardiol:右室功能障碍与STEMI患者远期预后不佳相关

2014-05-12 高晓方 译 医学论坛网

意大利一项研究表明,在接受冠脉血运重建的下壁STEMI患者中,右室功能障碍与远期预后恶化具有相关性。术后TIMI血流分级有助于预测右室功能障碍。论文于5月5日在线发表于《美国心脏病学杂志》(Am J Cardiol)。 此项研究共纳入141例行经皮冠脉介入并且右冠脉为梗死相关动脉的下壁STEMI患者。评估再灌注指数与右室功能障碍的相关性。利用TIMI血流、TFC、心肌显影分级(MBG)和ST段正

意大利一项研究表明,在接受冠脉血运重建的下壁STEMI患者中,右室功能障碍与远期预后恶化具有相关性。术后TIMI血流分级有助于预测右室功能障碍。论文于5月5日在线发表于《美国心脏病学杂志》(Am J Cardiol)。

此项研究共纳入141例行经皮冠脉介入并且右冠脉为梗死相关动脉的下壁STEMI患者。评估再灌注指数与右室功能障碍的相关性。利用TIMI血流、TFC、心肌显影分级(MBG)和ST段正常评估心肌再灌注。

结果显示,共有58例(41.1%)患者伴有右室功能障碍。右室功能障碍患者更有可能出现术后TIMI血流分级、TFC和MBG欠佳。ST段正常与否对右室功能障碍发生率无影响。随访2年时,右室功能障碍患者的心源性死亡、再次心梗和支架血栓形成发生率均升高。多变量分析显示,仅术后TIMI 3级与右室功能障碍相关。术后TIMI 3级排除右室功能障碍的特异性(74.5%)和阴性预测值(71%)均较高,而敏感性则有限(52%)。

原始出处:


Raffaele Piccolo, Tullio Niglio, Letizia Spinelli, Ernesto Capuano, Teresa Strisciuglio, Carolina D’Anna, Stefania De Luca, Dario Leosco, Antonio Rapacciuolo, Plinio Cirillo, Eugenio Stabile, Giovanni Esposito, Bruno Trimarco, Federico Piscione, Gennaro Galasso.Reperfusion Correlates and Clinical Outcomes of Right Ventricular Dysfunction in Patients with Inferior ST-segment Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention. Am J Cardiol May 05 2014. 


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