日本开发验血检查早老性痴呆症法 可助降低诊费

2018-02-01 周思敏 环球网

日本研究团队宣布开发出通过验血调查早老性痴呆症原因的检查方法,未来这可能会使诊症价格变得便宜,更有望用于发病前调查患病风险。

据香港“东网”2月1日报道,日本爱知县的国立长寿医疗研究中心和京都市岛津制作所等团队1月31日在英国科学杂志《自然》网络版上发表研究成果,宣布开发出通过验血调查早老性痴呆症原因的检查方法,相信这会令诊症价格变得便宜,甚至可能出现商机。而未来更有望用于发病前调查患病风险。

早老性痴呆症的原因众说纷纭。大脑内的β-淀粉样蛋白异常积存被视为原因之一。积存可能从发病的二三十年前开始,积有之人就算没有症状,未来发病的可能性也会升高。

目前医院是通过大型正电子发射断层成像装置(PET),或向腰部刺入长针抽取脑脊髓液调查是否有β-淀粉样蛋白积存,但费用高昂。

该团队开发的检查手法,则是用被称为抗体的蛋白质,从0.5毫升的血液中分离β-淀粉样蛋白相关物质,运用岛津制作所高级研究员、诺贝尔化学奖得主田中耕一等人开发的质量分析技术展开调查。被分离出来的相关物质有三种,从这三种物质的量的占有比率,可以知道β-淀粉样蛋白是否积存。

团队又以以日本和澳大利亚的60岁至90岁男女、共232人为研究对象,当中包括早老性痴呆症患者和健康人群,结果约9成的人与PET检查结果一致。

该团队透露,很久以前就持续开发这种方法,这次进行大规模研究后,确认能以高精确度判定结果。岛津制作所表示,今后打算向制药公司和研究人员提供分析血液的服务。而长寿医疗研究中心所长柳泽胜彦则表示,未来若能治疗和预防早老性痴呆症,这种手法也许可在高龄人士的诊症中广泛使用。

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    2018-05-26 Boyinsh
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    2018-02-03 Luyuxie_11