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Sci Rep：纳米羟基磷灰石的加入可显著改善葡聚糖-壳聚糖复合支架的理化性质

2018-09-12 MedSci MedSci原创

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将纳米羟基磷灰石掺入葡聚糖/壳聚糖的聚合物基质中，通过冷冻干燥技术获得新型复合支架。合成的复合支架通过不同的性能识别，如：X射线衍射（XRD），傅里叶变换红外光谱（FT-IR）和扫描电子显微镜（SEM）。 结果显示，葡聚糖和壳聚糖之间形成复合物，在聚合物基质内有大量的nHA分散。SEM图像显示支架内存在互连的孔结构。通过向葡聚糖/壳聚糖的聚合物基质中添加纳米羟基磷灰石，发现复合材料的孔隙率从

将纳米羟基磷灰石掺入葡聚糖/壳聚糖的聚合物基质中，通过冷冻干燥技术获得新型复合支架。合成的复合支架通过不同的性能识别，如：X射线衍射（XRD），傅里叶变换红外光谱（FT-IR）和扫描电子显微镜（SEM）。

结果显示，葡聚糖和壳聚糖之间形成复合物，在聚合物基质内有大量的nHA分散。SEM图像显示支架内存在互连的孔结构。通过向葡聚糖/壳聚糖的聚合物基质中添加纳米羟基磷灰石，发现复合材料的孔隙率从82％降低至67％。通过压缩试验测量支架的机械性能。所得结果证实，nHA的存在可显著提高复合支架的杨氏模量和抗压强度。

综上所述，该研究结果表明，研究所合成的复合材料可作为骨组织工程应用的良好候选者。

原始出处：

Emad El-Meliegy, N. I. Abu-Elsaad, et al., Improvement of physico-chemical properties of dextran-chitosan composite scaffolds by addition of nano-hydroxyapatite. Sci Rep. 2018; 8: 12180.

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    2019-01-10 dinorsor524

    #纳米羟基磷灰石#

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    2018-09-14 smartxiuxiu

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    2018-09-13 dlwang_26703132

    #壳聚糖#

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    2018-09-13 爆笑小医

    #羟基磷灰石#

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