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EASD 2014：血尿酸水平或影响胱抑素C水平

2014-09-15 高晓方 译 医学论坛网

血尿酸水平胱抑素CEASD2014
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欧洲糖尿病研究学会(EASD)2014年会的一项报告表明，在2型糖尿病患者中，血尿酸水平可能影响胱抑素C(cystatin-C)水平，并且独立于肾小球滤过率(GFR)。 此项横断面研究共纳入560例年龄为65.0±10.0岁的2型糖尿病患者。利用51Cr-EDTA测定GFR(mGFR)。将血清胱抑素C与数项临床和生化参数进行关联。通过多变量分析确定mGFR之外与血清胱抑素C水平独立相关性的因

欧洲糖尿病研究学会(EASD)2014年会的一项报告表明，在2型糖尿病患者中，血尿酸水平可能影响胱抑素C(cystatin-C)水平，并且独立于肾小球滤过率(GFR)。

此项横断面研究共纳入560例年龄为65.0±10.0岁的2型糖尿病患者。利用51Cr-EDTA测定GFR(mGFR)。将血清胱抑素C与数项临床和生化参数进行关联。通过多变量分析确定mGFR之外与血清胱抑素C水平独立相关性的因素。

结果显示，胱抑素C与mGFR、年龄、ACR白蛋白肌酐比、尿酸、白蛋白和血红蛋白具有显著相关性。血清胱抑素C水平与糖尿病持续时间、性别、降糖治疗、BMI、空腹血糖、HbA1c、肝功能、血脂、甲状腺功能、白细胞、电解质和hsCRP无显著相关性。然而，在标准多元回归分析中，仅mGFR和尿酸为胱抑素C水平的独立预测因素。

原始出处：

Uric acid serum level affects serum level of cystatin C, independently of GFR, in patients with type 2 diabetes.pdf



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    2015-06-05 ljjj1053

    好好学习学习

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=26063, encodeId=d4892606302, content=好好学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ac181616815, createdName=ljjj1053, createdTime=Fri Jun 05 16:24:00 CST 2015, time=2015-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1690581, encodeId=4f0b1690581e1, content=<a href='/topic/show?id=5c472843a1' target=_blank style='color:#2F92EE;'>#ASD#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2843, encryptionId=5c472843a1, topicName=ASD)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4e8529069357, createdName=okhuali, createdTime=Mon Mar 30 18:08:00 CST 2015, time=2015-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20590, encodeId=166f20590fe, content=控制好糖尿病可能提高肝硬化患者的预后。, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:14:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20591, encodeId=704720591b8, content=控制好糖尿病可能提高肝硬化患者的预后。, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:14:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1344409, encodeId=a127134440934, content=<a href='/topic/show?id=9437890692b' target=_blank style='color:#2F92EE;'>#血尿酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89069, encryptionId=9437890692b, topicName=血尿酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=96f62500201, createdName=12498e67m28暂无昵称, createdTime=Wed Sep 17 00:08:00 CST 2014, time=2014-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1446928, encodeId=9c9a1446928d6, content=<a href='/topic/show?id=259d8906e50' target=_blank style='color:#2F92EE;'>#血尿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89067, encryptionId=259d8906e50, topicName=血尿)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Wed Sep 17 00:08:00 CST 2014, time=2014-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1534075, encodeId=673015340e50d, content=<a href='/topic/show?id=576e643634' target=_blank style='color:#2F92EE;'>#EASD#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6436, encryptionId=576e643634, topicName=EASD)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21f812527653, createdName=qilu_qi, createdTime=Wed Sep 17 00:08:00 CST 2014, time=2014-09-17, status=1, ipAttribution=)]
    2015-03-30 okhuali

    #ASD#

    0

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    2015-04-11 x35042875

    控制好糖尿病可能提高肝硬化患者的预后。

    0

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    2015-04-11 x35042875

    控制好糖尿病可能提高肝硬化患者的预后。

    0

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    2014-09-17 12498e67m28暂无昵称

    #血尿酸#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=26063, encodeId=d4892606302, content=好好学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ac181616815, createdName=ljjj1053, createdTime=Fri Jun 05 16:24:00 CST 2015, time=2015-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1690581, encodeId=4f0b1690581e1, content=<a href='/topic/show?id=5c472843a1' target=_blank style='color:#2F92EE;'>#ASD#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2843, encryptionId=5c472843a1, topicName=ASD)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4e8529069357, createdName=okhuali, createdTime=Mon Mar 30 18:08:00 CST 2015, time=2015-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20590, encodeId=166f20590fe, content=控制好糖尿病可能提高肝硬化患者的预后。, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:14:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20591, encodeId=704720591b8, content=控制好糖尿病可能提高肝硬化患者的预后。, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:14:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1344409, encodeId=a127134440934, content=<a href='/topic/show?id=9437890692b' target=_blank style='color:#2F92EE;'>#血尿酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89069, encryptionId=9437890692b, topicName=血尿酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=96f62500201, createdName=12498e67m28暂无昵称, createdTime=Wed Sep 17 00:08:00 CST 2014, time=2014-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1446928, encodeId=9c9a1446928d6, content=<a href='/topic/show?id=259d8906e50' target=_blank style='color:#2F92EE;'>#血尿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89067, encryptionId=259d8906e50, topicName=血尿)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Wed Sep 17 00:08:00 CST 2014, time=2014-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1534075, encodeId=673015340e50d, content=<a href='/topic/show?id=576e643634' target=_blank style='color:#2F92EE;'>#EASD#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6436, encryptionId=576e643634, topicName=EASD)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21f812527653, createdName=qilu_qi, createdTime=Wed Sep 17 00:08:00 CST 2014, time=2014-09-17, status=1, ipAttribution=)]
    2014-09-17 quxin068

    #血尿#

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=26063, encodeId=d4892606302, content=好好学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ac181616815, createdName=ljjj1053, createdTime=Fri Jun 05 16:24:00 CST 2015, time=2015-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1690581, encodeId=4f0b1690581e1, content=<a href='/topic/show?id=5c472843a1' target=_blank style='color:#2F92EE;'>#ASD#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2843, encryptionId=5c472843a1, topicName=ASD)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4e8529069357, createdName=okhuali, createdTime=Mon Mar 30 18:08:00 CST 2015, time=2015-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20590, encodeId=166f20590fe, content=控制好糖尿病可能提高肝硬化患者的预后。, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:14:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20591, encodeId=704720591b8, content=控制好糖尿病可能提高肝硬化患者的预后。, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:14:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1344409, encodeId=a127134440934, content=<a href='/topic/show?id=9437890692b' target=_blank style='color:#2F92EE;'>#血尿酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89069, encryptionId=9437890692b, topicName=血尿酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=96f62500201, createdName=12498e67m28暂无昵称, createdTime=Wed Sep 17 00:08:00 CST 2014, time=2014-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1446928, encodeId=9c9a1446928d6, content=<a href='/topic/show?id=259d8906e50' target=_blank style='color:#2F92EE;'>#血尿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89067, encryptionId=259d8906e50, topicName=血尿)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Wed Sep 17 00:08:00 CST 2014, time=2014-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1534075, encodeId=673015340e50d, content=<a href='/topic/show?id=576e643634' target=_blank style='color:#2F92EE;'>#EASD#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6436, encryptionId=576e643634, topicName=EASD)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21f812527653, createdName=qilu_qi, createdTime=Wed Sep 17 00:08:00 CST 2014, time=2014-09-17, status=1, ipAttribution=)]
    2014-09-17 qilu_qi

    #EASD#

    0