J NATL CANCER I:科学家找到预测十年内乳腺癌复发的新方法 检测免疫“热点”可以预测乳腺癌复发的风险

2017-08-06 佚名 来宝网

科学家开发出了一种新的测试方法,可以找出高复发风险的乳腺癌乳腺癌女性,新的测试有助于更准确地评估癌症复发的风险,为他们提供监控或预防性治疗。

科学家开发出了一种新的测试方法,可以找出高复发风险的乳腺癌乳腺癌女性,新的测试有助于更准确地评估癌症复发的风险,为他们提供监控或预防性治疗。

伦敦癌症研究所的科学家们分析了来自1178名妇女的组织样本,她们均为最常见的乳腺癌雌激素受体阳性乳腺癌。

研究人们创建了一个新的,完全自动化的计算机工具来分析样本,比较了两种激素疗法,有助于阻止癌症手术后的复发。

研究人员发现,当免疫细胞聚集在一起的热点地区的时候,10年内复发的机会会高出25%。研究人员先前观察肿瘤雌激素受体阴性乳腺癌样本,发现这里聚类的免疫细胞有相反的效果,复发的几率较低。这项研究发表在《美国国家癌症研究所杂志》上,一旦新的测试通过验证,就可以用来帮助预测癌症复发的风险,并决定合适的治疗方法。
研究人员表示:“我们已经开发出一种新的自动化计算机工具可以评估出乳腺癌患者10年内的癌症复发风险,目前,我们研究中使用的样本已经形成常规临床实践的一部分,这意味着实现免疫热点测试会相对容易,成本较低,这种独创的新计算机自动测试分析乳腺癌样本,揭示了人眼在显微镜下不可能发现的模式,在未来,这种测试可以让我们确定哪些患者在激素治疗后复发的风险更高,并制定有可能改变复发的治疗方案。

原始出处:
Andreas Heindl,Ivana Sestak ,Kalnisha Naidoo,et al. Relevance of Spatial Heterogeneity of Immune Infiltration for Predicting Risk of Recurrence After Endocrine Therapy of ER+ Breast Cancer.JNCI: Journal of the National Cancer Institute, Volume 110, Issue 2, 1 February 2018, djx137, https://doi.org/10.1093/jnci/djx137 Published: 04 August 2017

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    2018-05-25 liye789132251
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    2018-06-15 qidongfanjian
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    2017-08-07 doctorJiangchao

    继续学习。

    0

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    2017-08-07 189****7206

    学习了谢谢分享

    0

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    2017-08-07 Julie W

    研究人员表示:“我们已经开发出一种新的自动化计算机工具可以评估出乳腺癌患者10年内的癌症复发风险,目前,我们研究中使用的样本已经形成常规临床实践的一部分,这意味着实现免疫热点测试会相对容易,成本较低,这种独创的新计算机自动测试分析乳腺癌样本,揭示了人眼在显微镜下不可能发现的模式,在未来,这种测试可以让我们确定哪些患者在激素治疗后复发的风险更高,并制定有可能改变复发的治疗方案。

    0

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    2017-08-07 李东泽

    很好,不错,以后会多学习

    0

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    2017-08-06 luominglian113

    学习了,谢谢分享

    0

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    2017-08-06 1dd8c52fm63(暂无匿称)

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