Obesity Science & Practice:机体维生素D水平影响其减肥手术的效果

2015-12-27 QQduph 译 MedSci原创

维生素D在机体内的作用很多,功能很强大,它可以帮助维持骨骼健康,修护免疫系统功能、有利于肺部和心脏健康。暴露在阳光下是机体合成维生素D并保持其水平在正常范围内的关键因素,太阳光紫外线辐射有助于体内维生素D的合成。因此,接受日光照射较少的民众往往机体内的维生素D水平较低,并出现众多的健康问题。发表在Obesity Science&Practice的一项杂志表明,若民众维生素D水平较低,则减肥

维生素D在机体内的作用很多,功能很强大,它可以帮助维持骨骼健康,修护免疫系统功能、有利于肺部和心脏健康。暴露在阳光下是机体合成维生素D并保持其水平在正常范围内的关键因素,太阳光紫外线辐射有助于体内维生素D的合成。因此,接受日光照射较少的民众往往机体内的维生素D水平较低,并出现众多的健康问题。发表在Obesity Science&Practice的一项杂志表明,若民众维生素D水平较低,则减肥手术的效果并不佳。 


约翰霍普金斯减肥手术中心的Leigh Peterson和同事们发现,在美国,在冬天接受减肥手术(此时机体维生素D水平最低)相比夏天进行减肥手术的民众而言更有可能出现并发症。
此外,研究人员发现美国北部(这里阳光较少)民众减肥手术后的效果相比美国南部(阳光充足)而言效果更差。 

阳光照射对维生素D的合成至关重要,所以生活在美国北部这一阳光不充足地区的民众患有维生素D缺乏症并不奇怪。因此,日光照射对维生素D水平和减肥手术的效果十分重要。

研究人员对932091名平均年龄为43岁、且于2001-2010年间接受减肥手术的美国民众进行了调查。他们比较了在冬天(1-3月)、夏天(7-9月)和春/秋季(10-12月和4-6月)三个不同记季节接受减肥手术的民众的减肥效果进行了对比。

减肥手术的不良结果十分少见,只有不到1%的患者出现感染。住院时间延长(定义为住院时长超过3天)这一结果较为普遍,约40%的民众都会出现。研究人员发现,住在卡罗莱纳州北部地区的减肥手术民众的民众更有可能出现感染或住院时间延长这两大常见不良后果。 

北部各州的民众相比南部各州,住院时间延长者超过15万人。该研究中一共有约30万民众出现住院时间延长,研究人员指出,约71%的术后并发症发生在北部各州。此外,研究人员发现,伤口感染、伤口愈合不全、伤口愈合时间延长等术后并发症较多发生在冬季接受减肥手术的民众。
 
研究人员认为,这些发现表明,机体维生素D水平可能影响接受减肥手术的患者的术后结果,因此他们建议患者应于术前预防性使用维生素D补充剂以减少患者术后并发症的发生。 

该研究的不足之处是研究人员并没有通过血清25(OH)D的浓度直接测量患者的维生素D水平,这或许对实验结果有一定的影响。此外,冬季的病原体可能更容易暴露和出现等因素也会影响实验结果。他们表示,仍需要进行更进一步的研究。

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    2016-04-23 智慧医人
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    2016-04-03 wincls
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    2016-01-08 andruhn

    好东西,值得分享,学习了!

    0

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    2015-12-29 jichang
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    2015-12-29 lingaifan
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    2015-12-29 skhzy

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