JAMA Intern Med:ACS患者胸痛在女性中更常见

2013-09-22 晓静 编译 医学论坛网

加拿大一项研究表明,急性冠脉综合征(ACS)患者最常见症状为胸痛。尽管女性比男性患者更不可能出现胸痛,但无胸痛表现与冠心病严重度标志物并无关联。相关论文9月16日在线发表于《美国医学会杂志·内科学》(JAMA Intern Med)。【原文阅读】 年轻ACS患者的临床表现是否有性别差异以及何种因素决定了无胸痛表现至今尚未明确。该研究旨在评估ACS表现的性别差异,年轻A

加拿大一项研究表明,急性冠脉综合征(ACS)患者最常见症状为胸痛。尽管女性比男性患者更不可能出现胸痛,但无胸痛表现与冠心病严重度标志物并无关联。相关论文9月16日在线发表于《美国医学会杂志·内科学》(JAMA Intern Med)。【原文阅读】

年轻ACS患者的临床表现是否有性别差异以及何种因素决定了无胸痛表现至今尚未明确。该研究旨在评估ACS表现的性别差异,年轻ACS无胸痛患者与性别、社会人口统计学、性别特征、社会心理和临床因素以及冠心病标志的相关性。

该项前瞻性队列研究共纳入1015例因ACS入院、年龄≤55岁的患者(30%为女性)。入院期间对患者的麦克斯威尼(McSweeney)急性和前驱性心肌梗死症状进行管理。

结果显示,两种性别的中位年龄为49岁。与男性患者相比,女性更可能发生非ST段抬高性心肌梗死,并且更可能无胸痛表现(P=0.03)。无胸痛表现的患者总体症状较少,且未发现无胸痛症状的可识别模式。在多变量模型中,女性和心动过速与无胸痛的ACS独立相关(P =0 .009)。无胸痛表现的患者在ACS类型、肌钙蛋白水平或冠脉狭窄方面与有胸痛患者无显著差异。

原文阅读

Khan NA, Daskalopoulou SS, Karp I, Eisenberg MJ, Pelletier R, Tsadok MA, Dasgupta K, Norris CM, Pilote L; for the GENESIS PRAXY Team.Sex Differences in Acute Coronary Syndrome Symptom Presentation in Young Patients.JAMA Intern Med. 2013 Sep 16.



    

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    2013-09-24 yaanren
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