EAU:实施积极检测成为治疗前列腺癌新方法!

2016-04-28 MedSci MedSci原创

在慕尼黑举行的欧洲泌尿外科协会会议上,Venderbos和同事提出了对427名接受根治性前列腺切除术、放疗、积极监测等治疗的患者的相关数据。他们使用有效的问卷调查评估5-10年前治疗前列腺癌的患者,同时对一些没有患前列腺癌的民众也进行了随访。他们发现,即积极监测相比手术和放疗治疗前列腺癌更能提高男性的泌尿系统和性功能。 积极监测是指主动监测前列腺癌的进程,在出现肿瘤进展或临床症状明显时给予治疗,即

在慕尼黑举行的欧洲泌尿外科协会会议上,Venderbos和同事提出了对427名接受根治性前列腺切除术、放疗、积极监测等治疗的患者的相关数据。他们使用有效的问卷调查评估5-10年前治疗前列腺癌的患者,同时对一些没有患前列腺癌的民众也进行了随访。他们发现,即积极监测相比手术和放疗治疗前列腺癌更能提高男性的泌尿系统和性功能。

积极监测是指主动监测前列腺癌的进程,在出现肿瘤进展或临床症状明显时给予治疗,即观察被选择的患者,预测那些今后会进展的患者并在还能治愈的时机实行根治性治疗干预。即不同于以往的姑息性疗法,试验过程中密切注意患者的疾病进程,如临床症状、组织学变化以及PSA水平的变化,同时选择性给予相对滞后一点的治疗。

研究人员比较了四个种族,同时选取没有患前列腺癌的男性对照者。他们发现,采用积极监测方式治疗的前列腺癌患者与对照组的生活质量相似。

但是其他专家认为这项研究有一定的局限性。首先,他们进行问卷调查后患者有可能参加各种治疗。其次,在不同的时期进行不同的问卷调查评估,得出的结果可能是不同的。但整体差异仍非常显著。此外,研究参与人员超过600人,符合率为65%-70%。由于某些人未完成调查,因此可能导致研究存在某些偏差。

实施积极检测有助于使患者明确其对生活的期待,并能在治疗若干年后实现他们的计划或愿望。但是许多人认为不能得到及时治疗因此会出现一定的心理问题,但事实上实施积极检测方法并不影响患者的生活质量。我们可以通过主动监测掌握患者的病情信息,且尊重患者,让他们知情并得知实施某些并发症(如尿失禁)和手术或放疗的风险。 


原始出处: 

Patient QoL: More Proof That PCa Surveillance Is a 'Reasonable Approach',Medscape,28,Apr,2016 http://www.medscape.com/viewarticle/861941">Patient QoL: More Proof That PCa Surveillance Is a 'Reasonable Approach',Medscape,28,Apr,2016


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    2016-05-24 839640778
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    2016-10-03 1e10c84am36(暂无匿称)

    深度好文,值得关注

    0

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    2016-06-09 Wuhuayan

    期待更多治疗方法

    0

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