Stroke : 脑中风后,血压管理,存在种族差异

2021-09-07 Freeman MedSci原创

与有或无卒中的白人成年人相比,黑人控制血压的比例较低,

高血压是脑卒中的主要危险因素,是美国女性死亡的第三大原因,男性死亡的第五大原因。高血压被认为是首次或复发中风的最重要的危险因素。如果高血压得到治疗和控制,中风基本上是可以预防的。

许多随机对照试验表明,降低血压(BP)可以减少中风的风险。与白人成年人相比,普通人群中的黑人成年人控制血压的可能性较低。

2014年美国心脏协会(AHA)/美国卒中协会指南建议,对于以前接受过治疗的神经系统稳定者,在急性卒中后恢复降压药物治疗,对于收缩压(SBP)≥140毫米汞柱或舒张压(DBP)≥90毫米汞柱者启动降压药物治疗。

与以前的指南相比,2017年美国心脏病学院(ACC)/AHA血压指南为有中风史的成年人设定了较低的血压目标,即SBP/DBP<130/80 mm Hg。

很少有研究使用2017年ACC/AHA血压指南的阈值来评估卒中幸存者中血压控制的种族差异。

藉此,University of Alabama的Oluwasegun P. Akinyelure等人,利用2017年ACC/AHA血压指南的阈值来研究中风后血压控制的种族差异。

为了进行比较,他们还研究了未发生中风的参与者在血压控制方面的种族差异。为了实现这些目标,他们分析了REGARDS(Reasons for Geographic and Racial Differences in Stroke )研究的数据。并假设,与有或无中风史的白人成年人相比,黑人控制血压的可能性较低。


他们研究了在基线(2003-2007年)和第二次随访(2013-2016年)期间服用抗高血压药物的参与者,他们是否经历过中风(分别为306人和7693人)。

第二次随访时的血压控制被定义为收缩压<130毫米汞柱和舒张压<80毫米汞柱,但年龄≥65岁的低风险成人(即没有糖尿病、慢性肾病、血管疾病史,且10年预测动脉粥样硬化性心血管疾病风险<10%的人)除外,他们的血压控制被定义为收缩压<130毫米汞柱。

在有中风史的参与者中,50.3%的白人参与者控制了血压,而黑人参与者为39.3%。在没有中风史的参与者中,56.0%的白人参与者控制了血压,而黑人参与者为50.2%。

经过多变量调整后,黑人参与者比白人参与者更不可能控制血压(有中风史的参与者的流行率为0.77[95%CI,0.59-1.02],无中风史的参与者为0.92[95%CI,0.88-0.97])。

这个研究的重要意义在于发现了:与有或无卒中的白人成年人相比,黑人控制血压的比例较低,经多变量调整后无统计学意义的差异。


原文出处:
Akinyelure OP, Jaeger BC, Moore TL, et al. Racial Differences in Blood Pressure Control Following Stroke: The REGARDS Study. Stroke. Published online September 2, 2021. doi:10.1161/STROKEAHA.120.033108

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  6. [GetPortalCommentsPageByObjectIdResponse(id=1344341, encodeId=311513443410f, content=<a href='/topic/show?id=683a88964b0' target=_blank style='color:#2F92EE;'>#血压管理#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88964, encryptionId=683a88964b0, topicName=血压管理)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=793a2500200, createdName=12498e5fm12(暂无昵称), createdTime=Thu Sep 09 20:53:10 CST 2021, time=2021-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1353597, encodeId=3376135359e77, content=<a href='/topic/show?id=29e1e4781f1' target=_blank style='color:#2F92EE;'>#种族差异#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74781, encryptionId=29e1e4781f1, topicName=种族差异)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Sep 09 20:53:10 CST 2021, time=2021-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1015952, encodeId=387e1015952fc, content=已学, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a2cd5528102, createdName=ms4000001358121555, createdTime=Thu Sep 09 08:33:35 CST 2021, time=2021-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1015912, encodeId=117e1015912a1, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=df324723890, createdName=452946589, createdTime=Wed Sep 08 23:36:50 CST 2021, time=2021-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1015668, encodeId=cb7d101566898, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bca95597359, createdName=ms9000000893312717, createdTime=Wed Sep 08 12:40:11 CST 2021, time=2021-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1015615, encodeId=0e7d1015615be, content=已了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210924/4ea70a3dcb1c45f5b79c619208e50ed3/e5680d86f38c4e86b9c69a138ea6aaa2.jpg, createdBy=61ad2443812, createdName=123de590m20暂无昵称, createdTime=Wed Sep 08 10:51:12 CST 2021, time=2021-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046120, encodeId=12f1104612025, content=中风是俗称,应该称为缺血性卒中吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=guging, createdTime=Wed Sep 08 08:53:10 CST 2021, time=2021-09-08, status=1, ipAttribution=)]
    2021-09-08 123de590m20暂无昵称

    已了解

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1344341, encodeId=311513443410f, content=<a href='/topic/show?id=683a88964b0' target=_blank style='color:#2F92EE;'>#血压管理#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88964, encryptionId=683a88964b0, topicName=血压管理)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=793a2500200, createdName=12498e5fm12(暂无昵称), createdTime=Thu Sep 09 20:53:10 CST 2021, time=2021-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1353597, encodeId=3376135359e77, content=<a href='/topic/show?id=29e1e4781f1' target=_blank style='color:#2F92EE;'>#种族差异#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74781, encryptionId=29e1e4781f1, topicName=种族差异)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Sep 09 20:53:10 CST 2021, time=2021-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1015952, encodeId=387e1015952fc, content=已学, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a2cd5528102, createdName=ms4000001358121555, createdTime=Thu Sep 09 08:33:35 CST 2021, time=2021-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1015912, encodeId=117e1015912a1, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=df324723890, createdName=452946589, createdTime=Wed Sep 08 23:36:50 CST 2021, time=2021-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1015668, encodeId=cb7d101566898, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bca95597359, createdName=ms9000000893312717, createdTime=Wed Sep 08 12:40:11 CST 2021, time=2021-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1015615, encodeId=0e7d1015615be, content=已了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210924/4ea70a3dcb1c45f5b79c619208e50ed3/e5680d86f38c4e86b9c69a138ea6aaa2.jpg, createdBy=61ad2443812, createdName=123de590m20暂无昵称, createdTime=Wed Sep 08 10:51:12 CST 2021, time=2021-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046120, encodeId=12f1104612025, content=中风是俗称,应该称为缺血性卒中吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=guging, createdTime=Wed Sep 08 08:53:10 CST 2021, time=2021-09-08, status=1, ipAttribution=)]
    2021-09-08 guging

    中风是俗称,应该称为缺血性卒中吧

    0

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