J Thromb Haemost:CHADS2评分和CHA2 DS2 -VASc评分可预测非房颤患者卒中的发生

2016-05-30 phylis 译 MedSci原创

背景:CHADS2评分和CHA2 DS2 VASc评分可用于房颤(AF)患者预测卒中发生。研究者旨在检测这些分数预测非房颤患者卒中发生的性能。方法:研究者应用以色列最大的HMO计算机化的数据库,研究者在2012年1月所有非抗凝的成人,年龄在50岁以上。随访到2014年12月31号卒中或TIA的发生。结果:基线时1053871人没有AF;在随访3014002人年,34215发生卒中/TIA(脑卒中/

背景:CHADS2评分和CHA2 DS2 VASc评分可用于房颤(AF)患者预测卒中发生。研究者旨在检测这些分数预测非房颤患者卒中发生的性能。

方法:研究者应用以色列最大的HMO计算机化的数据库,研究者在2012年1月所有非抗凝的成人,年龄在50岁以上。随访到2014年12月31号卒中或TIA的发生。

结果:基线时1053871人没有AF;在随访3014002人年,34215发生卒中/TIA(脑卒中/TIA的发病率,1.14每100人年)。随着CHADS2评分升高,脑卒中/短暂性脑缺血发作的发病率按照级别方式升高:CHADS2评分0到6分,发病率分别为0.36,0.89,1.89,2.96,4.31,5.37,和6.62每100人年。CHA2 DS2 -VASc评分结果相似。基线有AF的46657例患者,卒中/TIA发生存在类似的按级别上升的趋势;然而,与无AF的人相比,每个得分阶层卒中/TIA发生率较高。无房颤的CHADS2和CHA2 DS2 -VASc评分的ROC曲线下面积分别为0.718(95% CI,0.715-0.721)和0.714(0.711-0.717),房颤患者的分别为0.606(0.598-0.614)和0.610(0.602-0.618)。

结论:与房颤患者相比,CHADS2评分和CHA2 DS2 -VASc评分预测无房颤卒中/TIA具有相对高性能。

原始出处:

Saliba W, Gronich N, et al. The role of CHADS2 and CHA2 DS2 -VASc scores in the prediction of stroke in individuals without atrial fibrillation: a population-based study. J Thromb Haemost. 2016 Apr 1.


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    2017-01-31 changfy
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    2016-11-04 huperzia
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    2016-10-14 ylzr123

    赞了,认真探究、学习。

    0

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    2016-06-11 quxin068
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WCC 2014:CHADS2评分可预测房颤导管消融患者并发症?

首都医科大学附属北京安贞医院马长生、董建增等探讨了CHADS2评分系统是否可以预测接受导管消融治疗房颤患者的并发症,结果表明,CHADS2评分能够有效预测上述患者的并发症。 此项回顾性研究共纳入251例接受导管消融的房颤患者。就计算CHADS2而言,以卒中或短暂性脑缺血发作病史计2分,以年龄≥65岁、高血压病史、糖尿病、近期心衰分别计1分。评估CHADS2评分能否在导管消融房颤患者中预测并发症。