Ann Throac Surg:一种新的瓣保留主动脉根部置换术

2013-04-24 Ann Throac Surg dy

复合移植置换术是治疗患有主动脉根部瘤并伴有主动脉瓣关闭不全病人的传统手段。但是对于病人,选择这种手术意味着要忍受移植的生物或机械膜瓣所带来的不便。由于主动脉根部瘤并没有影响到主动脉瓣尖端,因此保留膜瓣的手术越来越受到青睐。近10年来,虽然David等人发明了多种效果较好的瓣保留主动脉根部置换术,但由于这些手术技术要求高、耗时长且容错率低,因此研究新的简易可行的方法以改进这种手术显得十分必要。来自福

复合移植置换术是治疗患有主动脉根部瘤并伴有主动脉瓣关闭不全病人的传统手段。但是对于病人,选择这种手术意味着要忍受移植的生物或机械膜瓣所带来的不便。由于主动脉根部瘤并没有影响到主动脉瓣尖端,因此保留膜瓣的手术越来越受到青睐。近10年来,虽然David等人发明了多种效果较好的瓣保留主动脉根部置换术,但由于这些手术技术要求高、耗时长且容错率低,因此研究新的简易可行的方法以改进这种手术显得十分必要。来自福建医科大学附属协和医院心外科的陈良万博士等人研究了一种新的瓣保留主动脉根部置换术,研究结果发表在2013年4月的《胸外科年鉴》(The Annals of Thoracic Surgery)杂志上。作者发现这种方法比较容易重建主动脉根部构造且能有效地阻止出血。
研究者们首先通过主动脉窦壁折叠术以及去除一部分窦壁的方式对主动脉根部进行复位成形术。接来下,将三片大小形状和相应折叠后的主动脉窦适应的泪珠状的膜片缝合在主动脉窦内,形成新内膜。同时,原位上的冠状动脉孔与相应膜片上的小孔相连接。然后再通过吻合术将涤纶管接合到重建的主动脉根部,且涤纶管与植入膜片的远端边缘相结合。
研究者们通过一年多的临床试验,对9名患者实施了手术。这9名患者术后都没有发生出血或其他异常现象。其中5名患者在术后心脏超声检测中没有发现血液回流现象,而剩下4人只有轻微的回流。在接下来的7到31个月(平均20.2±9.8个月)的时间内,没有发生死亡现象,也没有病人需要重新接受手术。
该研究发现,将主动脉根部复位成形术与膜片移植技术联合起来的方法具有两种优点。第一,这种方法比较容易重建主动脉根部的结构。第二,该方法能有效的阻止出血。因此,该方法是一种可行的瓣保留主动脉根部置换技术。
主动脉相关的拓展阅读:


Valve-sparing root replacement with root reduction plasty and patch neointima placement.
Abstract
We describe an alternative valve-sparing aortic root replacement technique for patients with root aneurysms accompanied by aortic valve insufficiency. Aortic root reduction plasty was accomplished by plication and exclusion of parts of the sinus walls. Subsequently, 3 teardrop-shaped patches compatible with the sizes and shapes of the corresponding plicated sinuses were sutured inside the sinuses as neointima, and in situ coronary buttons were connected to the small holes created in the corresponding patches. A Dacron tube graft was then anastomosed to the reconstructed aortic root with incorporation of the distal margin of the implanted patches. Our initial application showed that this combined root reduction plasty and patch neointima placement is a feasible valve-sparing aortic root replacement technique. This combined technique easily restores the aortic root geometry and effectively prevents bleeding.

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    2013-06-08 yxch48
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